Mariya Moosajee

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Professor and Group Leader

The Francis Crick Institute

United Kingdom

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About

Professor Mariya Moosajee is a Group Leader at the Francis Crick Institute in the UK. Her research encompasses genetic factors in non-syndromic childhood glaucoma, the clinical spectrum of retinal diseases, and novel approaches to visual impairment care, including Charles Bonnet syndrome. Recent publications reflect her commitment to advancing ophthalmic research and developing innovative solutions for patients.

Recent Grants

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Unravelling the molecular complexity of ocular maldevelopment

Open Date: 2017-01-01

Close Date: 2022-01-01

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Designer aminoglycosides to treat nonsense-mediated inherited retinal disease

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Mapping the clinical phenotype of Choroideremia to identify an optimal therapeutic window for preventing sight loss- A UK multicentre deep phenotyping study

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Non viral gene therapy for Ushers Syndrome

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Articles (20)

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2022

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UNITED KINGDOM

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Lee Jones

University College London

UNITED KINGDOM

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Jo Huiqing Zhou

Radboud University

NETHERLANDS

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Mariya Moosajee

Research Interests

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Contact this professor

About

Recent Grants

Articles (20)

From research to action: Recommendations for Charles Bonnet syndrome care and policy

Charles Bonnet syndrome among visually impaired military veterans: findings from a UK screening and survey study

Genetic Basis of Non-Syndromic Childhood Glaucoma Associated with Anterior Segment Dysgenesis: A Narrative Review

DYRK1A syndrome presenting with a familial exudative vitreoretinopathy (FEVR)-like retinovascular phenotype

Charles Bonnet syndrome: taking another look at visual hallucinations in sight loss

Expanding the Clinical Spectrum of CRB1-Retinopathies: A Novel Genotype–Phenotype Correlation with Macular Dystrophy and Elevated Intraocular Pressure

Generation of a human iPSC line (UCLi025-A) from a patient with PHARC syndrome harbouring biallelic variants in ABHD12

Long-term natural history of ellipsoid zone width inUSH2A-retinopathy

Assessment of CRB1-Associated Retinopathies Using the S-MAIA Fast Protocol and Spectral-Domain Optical Coherence Tomography

User-Centred Design and Development of a Smartphone Application (<i>OverSight</i>) for Digital Phenotyping in Ophthalmology

Foveal Hypoplasia in CRB1-Related Retinopathies

Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs

Successful large gene augmentation of USH2A with non-viral episomal vectors

Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia

Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3): Role in Retinal Development and Disease

Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina

Identification of Novel Coloboma Candidate Genes through Conserved Gene Expression Analyses across Four Vertebrate Species

A Natural History Study of RP2-Related Retinopathy

Changes in Mitochondrial Size and Morphology in the RPE and Photoreceptors of the Developing and Ageing Zebrafish

Real-world clinical and molecular management of 50 prospective patients with microphthalmia, anophthalmia and/or ocular coloboma

Collaborators (7)

Holly Bridge

Eunice Sin Ying Tang

Jasleen Jolly

Peter Thomas

Joe Rainger

Lee Jones

Jo Huiqing Zhou

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