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Mark A. Rubin

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Professor

University of Bern

Switzerland

Research Interests

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Recent Grants

Grant: Open

Defining the Role of the SWI/SNF Chromatin Remodeling Complex in Advanced Metastatic Castration-Resistant Prostate Cancer (mCRPC) Therapy Resistance

Open Date: 2024-02-01

Close Date: 2027-01-01

Grant: Close

Toward novel therapies for PSMA non-eligible and non-responsive metastatic prostate cancer

Open Date: 2023-11-01

Close Date: 2025-10-01

Grant: Close

Towards a novel theranostics approach for AR-negative castration-resistant prostate cancer

Open Date: 2023-07-01

Close Date: 2026-06-01

Grant: Close

Leveraging poison introns for therapeutics and diagnostics of lethal prostate cancer

Open Date: 2022-12-01

Close Date: 2024-11-01

Grant: Close

Precision oncology approach towards understanding prostate cancer lineage plasticity

Open Date: 2022-07-01

Close Date: 2024-06-01

Articles (14)

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2026

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2026

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2025

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (14)

Gurpreet Kaur Arora

Staff Scientist

Sanford Burnham Prebys Medical Discovery Institute

UNITED STATES

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Andrej Benjak

Senior scientist - computational genomics

University of Bern

SWITZERLAND

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Jennie Jeyapalan

Associate Professor

University of Nottingham

UNITED KINGDOM

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Gary England

University of Nottingham

UNITED KINGDOM

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Nicholas Brady

Assistant Professor

Weill Cornell Medicine

UNITED STATES

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Anthony Gill

University of Sydney

AUSTRALIA

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Tomasz Michal Beer

Oregon Health & Science University

UNITED STATES

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Julijana Ivanisevic

Head of Metabolomics Unit / Senior Lecturer

University of Lausanne, Faculty of Biology and Medicine

SWITZERLAND

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Mark Arends

Professor of Pathology, Head of Division

University of Edinburgh

UNITED KINGDOM

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Charlotte K Y Ng

Group leader

Humanitas University

ITALY

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Simone de Brot

University of Bern

SWITZERLAND

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Salvatore Piscuoglio

Associate Professor

Humanitas University

ITALY

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Marika Lehner

University of Bern

SWITZERLAND

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Rolf I. Skotheim

Professor II

University of Oslo

NORWAY

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Mark A. Rubin

Research Interests

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Recent Grants

Articles (14)

The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics

Reversing—or Rewiring—Lineage Plasticity? Lessons from EZH2 Loss in Prostate Cancer

Loss of PI5P4Kα Slows the Progression of a Pten Mutant Basal Cell Model of Prostate Cancer

PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition.

Comparative pathology of dog and human prostate cancer

Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.

Lineage plasticity in prostate cancer: Looking beyond intrinsic alterations

Clinical application of advanced multi-omics tumor profiling: Shaping precision oncology of the future

The evolving landscape of prostate cancer somatic mutations

A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients

Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies

Corrigendum to “What Experts Think About Prostate Cancer Management During the COVID-19 Pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021” [Eur Urol 82(1):6–11] (European Urology (2022) 82(1) (6–11), (S0302283822016505), (10.1016/j.eururo.2022.02.010))

Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors

Histological and immunohistochemical investigation of canine prostate carcinoma with identification of common intraductal carcinoma component.

Collaborators (14)

Gurpreet Kaur Arora

Andrej Benjak

Jennie Jeyapalan

Gary England

Nicholas Brady

Anthony Gill

Tomasz Michal Beer

Julijana Ivanisevic

Mark Arends

Charlotte K Y Ng

Simone de Brot

Salvatore Piscuoglio

Marika Lehner

Rolf I. Skotheim

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