Mark C. Williams

Professor

Northeastern University

United States

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About

Mark C. Williams is a Professor at Northeastern University in the United States. His research focuses on various aspects of molecular biology, particularly in relation to viral proteins, DNA interactions, and protein dynamics. Recent publications include investigations into HIV-1 nucleocapsid protein, DNA intercalators, and the structural properties of nucleic acid-bound complexes. Professor Williams's work contributes valuable insights into genomic stability and protein-nucleic acid interactions.

Articles (12)

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2020

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2020

Collaborators (2)

Akira Ono

University of Michigan Medical School

UNITED STATES

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Megan Nunez

Schow Professor in the Physical and Natural Sciences

Wellesley College

UNITED STATES

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Mark C. Williams

Research Interests

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Articles (12)

Cationic Residues of the HIV-1 Nucleocapsid Protein Enable DNA Condensation to Maintain Viral Core Particle Stability during Reverse Transcription

Mechanism of DNA Intercalation by Chloroquine Provides Insights into Toxicity

DNA damage alters binding conformations of E. coli single-stranded DNA-binding protein

Dynamic structure of T4 gene 32 protein filaments facilitates rapid noncooperative protein dissociation

Structural domains of SARS-CoV-2 nucleocapsid protein coordinate to compact long nucleic acid substrates

Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes

Left versus right: Exploring the effects of chiral threading intercalators using optical tweezers

HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating

The L1-ORF1p coiled coil enables formation of a tightly compacted nucleic acid-bound complex that is associated with retrotransposition

Multiprotein E. coli SSB-ssDNA complex shows both stable binding and rapid dissociation due to interprotein interactions

Significant Differences in RNA Structure Destabilization by HIV-1 GagDp6 and NCp7 Proteins.

Introduction to Special Issue “The 11th International Retroviral Nucleocapsid and Assembly Symposium”

Collaborators (2)

Akira Ono

Megan Nunez

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