Mark K. Wax

Objective The aim of the study was to determine outcomes after interventional radiology treatment of carotid blowout. Methods Patients with head and neck cancer and who received interventional radiology treatment for carotid blowout between 2000 and 2022 were included. Pre‐treatment, treatment, and post‐treatment variables were evaluated. Results Fourteen patients met inclusion criteria. Eleven patients (78.6%) had a history of radiation. Twelve (85.7%) blowouts occurred within 6 months of recent intervention. Initial treatment was with stenting ( n = 9, 64.3%), coil embolization ( n = 4, 28.6%), or both ( n = 1, 7.1%). Six patients (42.9%) underwent subsequent carotid bypass. Morbidity following treatment included stroke ( n = 1) and rebleeding ( n = 4). Six‐month survival was 57.1%. Of the patients who survived past six months, 5/8 were treated with carotid bypass and coverage. Four patients died of cancer progression, three of rebleeding, and three of medical complications. Conclusion The majority of carotid blowout occurs within 6 months of surgery or radiation. Many who survive will die of cancer progression or medical illness. Carotid bypass with flap coverage may be a worthwhile treatment for carotid blowout and should be considered as an adjunct to endovascular treatment. Level of Evidence 4 Laryngoscope , 134:695–700, 2024