Mark Middleton

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University of Oxford

United Kingdom

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Recent Grants

Grant: Open

CRUK Oxford Centre

Open Date: 2022-04-01

Close Date: 2027-03-01

Grant: Close

Symplify Trial

Open Date: 2021-02-01

Close Date: 2024-03-01

Grant: Close

Permeabilisation of brain metastases for early and more effective treatment

Open Date: 2020-11-01

Close Date: 2024-12-31

Grant: Close

Permeabilisation of brain metastases for early detection and treatment

Open Date: 2016-06-30

Close Date: 2019-07-30

Grant: Close

Clinical Trial Research Fellowship

Open Date: 2015-06-01

Close Date: 2018-05-31

Articles (10)

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (12)

Thierry André

Sorbonne Université

FRANCE

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Orion Tong

UNITED KINGDOM

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Lennard Lee

Associate Professor

University of Oxford

UNITED KINGDOM

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James J Gilchrist

University of Oxford

UNITED KINGDOM

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Rebecca S. Kristeleit

University of Arizona College of Medicine

UNITED STATES

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Nicola R. Sibson

University of Oxford

UNITED KINGDOM

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Matthew Fittall

Honorary Associate Professor

University College London

UNITED KINGDOM

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Michael Dustin

Kennedy Trust Professor of Molecular Immunology

University of Oxford

UNITED KINGDOM

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Pia Osterlund

Karolinska University Hospital

SWEDEN

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Tim Robinson

University of Bristol

UNITED KINGDOM

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Paul E. Van Schil

BELGIUM

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Gary Middleton

Professor of Medical Oncology

University of Birmingham

UNITED KINGDOM

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Mark Middleton

Research Interests

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Recent Grants

Articles (10)

Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform distinct functional states within the regulatory and cytotoxic T cells.

Association of SARS-CoV-2 Spike Protein Antibody Vaccine Response With Infection Severity in Patients With Cancer: A National COVID Cancer Cross-sectional Evaluation.

Circulating galectin-1 delineates response to bevacizumab in melanoma patients and reprograms endothelial cell biology.

How Can the EU Beating Cancer Plan Help in Tackling Lung Cancer, Colorectal Cancer, Breast Cancer and Melanoma?

WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma.

A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer.

Adjuvant nivolumab versus ipilimumab (CheckMate 238 trial): Reassessment of 4-year efficacy outcomes in patients with stage III melanoma per AJCC-8 staging criteria.

VCAM-1-targeted MRI Improves Detection of the Tumor-brain Interface.

Treatment with a retinoic acid-inducible gene I (RIG-I) agonist as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors: results from two phase 1 studies.

Collaborators (12)

Thierry André

Orion Tong

Lennard Lee

James J Gilchrist

Rebecca S. Kristeleit

Nicola R. Sibson

Matthew Fittall

Michael Dustin

Pia Osterlund

Tim Robinson

Paul E. Van Schil

Gary Middleton

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