Mark O'Driscoll

Research Professor of Human Molecular Genetics

University of Sussex School of Life Sciences

United Kingdom

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Mark O'Driscoll is a Research Professor of Human Molecular Genetics at the University of Sussex School of Life Sciences in the UK. His research focuses on DNA repair mechanisms, congenital neutropenia, and the genetic underpinnings of breast cancer susceptibility. Recent publications include studies on Cyclophilin A's role in DNA repair, the impact of DBF4 mutations, and the importance of DTYMK in maintaining genome integrity.

Articles (4)

Year:

2024

Year:

2023

Year:

2023

Year:

2021

Collaborators (3)

Paul Kuentz

Professeur des Universités-Praticien Hospitalier

Centre Hospitalier Universitaire Vaudois

FRANCE

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Marjo S van der Knaap

Amsterdam University Medical Centers

NETHERLANDS

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Margaux Gerbaux

Université libre de Bruxelles

BELGIUM

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Mark O'Driscoll

Research Interests

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Articles (4)

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles

Homozygous DBF4 mutation as a cause of severe congenital neutropenia.

DTYMK is essential for genome integrity and neuronal survival.

Collaborators (3)

Paul Kuentz

Marjo S van der Knaap

Margaux Gerbaux

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