Mark S. Wolff

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Articles (16)

Year:

2025

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2024

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2024

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2024

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2024

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2024

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2024

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2023

Objectives U.S. and global estimates indicate that over 30% of adults fear receiving dental care, including over 20% who have visited a dentist in the last year, leading to avoidance and degraded oral and systemic health. Although evidence‐based cognitive‐behavioral treatments for dental fear (CBT‐DF) exist, they have little impact on the millions who seek dental care annually because they are not disseminable (6 h of in‐chair time, delivered only in person at a few sites). We developed a disseminable CBT‐DF stepped‐care treatment comprising (Step 1) a mobile‐health application and, for those who remain fearful, (Step 2) a 1‐h, one‐on‐one psychological treatment session that allows practice during exposure to the patient's most‐feared stimuli. We hypothesized that the treatment would (a) be rated highly on usability and credibility and (b) result in clinically consequential (i.e., lowering fear into the 0–3 “no/low fear” zone) and statistically significant changes in global dental fear. Method Racially/ethnically diverse patients ( N = 48) with moderate to severe dental fear were recruited; all completed Step 1, and n = 16 completed Step 2. Results As hypothesized, users found the stepped‐care treatment highly usable, credible, and helpful. Critically, this stepped‐care approach produced reductions in patients' dental fear that were both clinically consequential (with half no longer fearful) and statistically significant ( d = 1.11). Conclusions This usable, credible, stepped‐care approach to dental fear treatment holds promise for liberating evidence‐based CBT‐DF from specialty clinics, allowing broad dissemination.

Year:

2023

The COVID-19 pandemic has escalated the risk of SARS-CoV-2 transmission in the dental practice, especially as droplet-aerosol particles are generated by high-speed instruments. This has heightened awareness of other orally transmitted viruses, including influenza and herpes simplex virus 1 (HSV1), which are capable of threatening life and impairing health. While current disinfection procedures commonly use surface wipe-downs to reduce viral transmission, they are not fully effective. Consequently, this provides the opportunity for a spectrum of emitted viruses to reside airborne for hours and upon surfaces for days. The objective of this study was to develop an experimental platform to identify a safe and effective virucide with the ability to rapidly destroy oral viruses transported within droplets and aerosols. Our test method employed mixing viruses and virucides in a fine-mist bottle atomizer to mimic the generation of oral droplet-aerosols. The results revealed that human betacoronavirus OC43 (related to SARS-CoV-2), human influenza virus (H1N1), and HSV1 from atomizer-produced droplet-aerosols were each fully destroyed by only 100 ppm of hypochlorous acid (HOCl) within 30 s, which was the shortest time point of exposure to the virucide. Importantly, 100 ppm HOCl introduced into the oral cavity is known to be safe for humans. In conclusion, this frontline approach establishes the potential of using 100 ppm HOCl in waterlines to continuously irrigate the oral cavity during dental procedures to expeditiously destroy harmful viruses transmitted within aerosols and droplets to protect practitioners, staff, and other patients.

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2023

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2023

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2021

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2021

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2021

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2021

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2021

Collaborators (10)

Geelsu Hwang

University of Pennsylvania

UNITED STATES
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Laura Gibson

Research Assistant Professor

University of Pennsylvania

UNITED STATES
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Liviu Steier Dr.med.dent.

University of Pennsylvania

UNITED STATES
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R.P. Ricciardi

University of Pennsylvania

UNITED STATES
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Richard Heyman

Professor

New York University

UNITED STATES
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Zhong Zheng

UCLA School of Dentistry

UNITED STATES
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Kelly Daly

New York University

UNITED STATES
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Nandita Mitra

Professor, Clinician-Educator

University of Pennsylvania

UNITED STATES
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Katherine Theken

Assistant Professor

University of Pennsylvania

UNITED STATES
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Heather Cassie

Academic, Senior Lecturer

University of Dundee

UNITED KINGDOM
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