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Markéta Martínková

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Associate Professor (docent) of Biochemistry

Charles University in Prague

Czech Republic

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Professors in Biochemistry

About

Markéta Martínková is an Associate Professor of Biochemistry at Charles University in Prague, Czech Republic. Her research focuses on the role of heme in various biological systems, particularly in relation to tumor suppressor proteins and oxygen sensors. Recent publications include works on point-of-care detection methods for Streptococcus pneumoniae and investigations into kinase catalysis during lung cancer development.

Recent Grants

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Prevention of antibiotic resistance by TARGEted Treatment of pneumonia in children (TARGET)

Open Date: 2020-03-01

Close Date: 2023-02-01

Grant: Close

Molecular mechanisms of intraprotein/interdomain signal transduction in model heme sensor proteins

Open Date: 2015-01-01

Close Date: 2017-12-31

Grant: Close

Comparison of the adsorption capacity and trapping effectiveness of diosmectite and charcoal on the compounds causing the 10 most frequent intoxications in acute medicine - the pilot study

Open Date: 2014-01-01

Close Date: 2015-12-01

Articles (11)

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2025

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2020

Collaborators (3)

Alžběta Lengálová

Charles University, Faculty of Science

CZECH REPUBLIC

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Toru Shimizu

Professor Emeritus

Tohoku University

JAPAN

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D. Savchenko

Head of Department

national technical university of ukraine “igor sikorsky kyiv polytechnic institute”

UKRAINE

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Markéta Martínková

Research Interests

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About

Recent Grants

Articles (11)

Simplified Loop-Mediated Isothermal Amplification-Based Method for Point-of-Care Detection of Streptococcus pneumoniae in Low-Resource Settings

Is ATP the Only Nucleoside Triphosphate among ATP, CTP, GTP, and UTP to Have a Role in Kinase Catalysis of Heme-Regulated Inhibitor toward eIF2α during Lung Cancer Development?

Is ATP the Only Nucleoside Triphosphate among ATP, CTP, GTP, and UTP to Have a Role in Kinase Catalysis of Heme-Regulated Inhibitor toward eIF2 alpha during Lung Cancer Development?

Characterization of the interaction between the tumour suppressor p53 and heme and its role in the protein conformational dynamics studied by various spectroscopic techniques and hydrogen/deuterium exchange coupled with mass spectrometry

Hydrogen/Deuterium Exchange Mass Spectrometry of Heme-Based Oxygen Sensor Proteins

Monitoring the Kinase Activity of Heme-Based Oxygen Sensors and Its Dependence on O<sub>2</sub> and Other Ligands Using Phos-Tag Electrophoresis

Signal transduction mechanisms in heme-based globin-coupled oxygen sensors with a focus on a histidine kinase (AfGcHK) and a diguanylate cyclase (YddV or EcDosC)

Signal transduction mechanisms in heme-based globin-coupled oxygen sensors with a focus on a histidine kinase (AfGcHK) and a diguanylate cyclase (YddV or EcDosC)

The Novel Role of Heme in Health and Diseases – Heme-Containing Sensor Proteins

The Novel Role of Heme in Health and Diseases - Heme-Containing Sensor Proteins

Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction

Collaborators (3)

Alžběta Lengálová

Toru Shimizu

D. Savchenko

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