Markus Künzler

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Adjunct Professor

Eidgenössische Technische Hochschule Zürich

Switzerland

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Markus Künzler is an Adjunct Professor at Eidgenössische Technische Hochschule Zürich, Switzerland. His research areas encompass macrocyclic peptides, fungal biosynthesis, and peptide biology, as highlighted in his recent articles on peptide macrocyclization and mycorrhizal interactions. He is actively involved in studying the structural and functional properties of peptides derived from fungi, contributing to advancements in the understanding of natural product biosynthesis.

Recent Grants

Grant: Open

Cell biology of a mushrooms chemical defense against fungivorous nematodes

Open Date: 2023-01-01

Close Date: 2027-12-01

Grant: Close

Molecular dissection of the chemical defense system of multicellular fungi against predation

Open Date: 2017-08-01

Close Date: 2021-07-31

Grant: Close

Regulation, physiological significance and specificity of the chemical defense system of multicellular fungi against predation

Open Date: 2014-02-01

Close Date: 2017-07-31

Grant: Close

Molecular characterization of a protein-mediated defense of fungi against predators and parasites and its application for fighting animal parasitic nematodes

Open Date: 2010-06-01

Close Date: 2013-05-31

Grant: Close

Molecular mechanism of a galectin-mediated defense of a mushroom against nematodes

Open Date: 2007-05-01

Close Date: 2010-05-31

Articles (13)

Year:

2025

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Year:

2021

Collaborators (5)

Jonathan Plett

Senior Lecturer

University of Western Sydney

AUSTRALIA

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Andrew Giltrap

Lecturer

University of Technology, Sydney

AUSTRALIA

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Alvar Gossert

ETH Zürich

SWITZERLAND

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Jeffrey W. Bode

Nagoya University

JAPAN

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Julia A. Vorholt

Full Professor

Swiss Federal Institute of Technology in Zurich

SWITZERLAND

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Markus Künzler

Research Interests

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About

Recent Grants

Articles (13)

Macrocyclization of backbone N-methylated peptides by a prolyl oligopeptidase with a distinctive substrate recognition mechanism

Promiscuity of Omphalotin A Biosynthetic Enzymes Allows de novo Production of Non‐Natural Multiply Backbone N‐Methylated Peptide Macrocycles in Yeast

Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes

Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability

Mycorrhiza‐induced mycocypins of Laccaria bicolor are potent protease inhibitors with nematotoxic and collembola antifeedant activity

Structural and Functional Analysis of Peptides Derived from KEX2-Processed Repeat Proteins in Agaricomycetes Using Reverse Genetics and Peptidomics

Author Correction: Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A

Genome sequences of Rhizopogon roseolus, Mariannaea elegans, Myrothecium verrucaria, and Sphaerostilbella broomeana and the identification of biosynthetic gene clusters for fungal peptide natural products

Injection into and extraction from single fungal cells

Marasmius oreades agglutinin enhances resistance of Arabidopsis against plant-parasitic nematodes and a herbivorous insect

Cytoplasmic Lipases—A Novel Class of Fungal Defense Proteins Against Nematodes

Author Correction: Identifcation, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A

Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A

Collaborators (5)

Jonathan Plett

Andrew Giltrap

Alvar Gossert

Jeffrey W. Bode

Julia A. Vorholt

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