Martin Degen

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Lab Head

University of Bern

Switzerland

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About

Martin Degen is a Lab Head at Universität Bern, Switzerland. His research focuses on osteogenesis, tissue engineering, and the molecular mechanisms underlying cleft lip and palate. Recent publications highlight his work on fibroblast behavior in cleft lip tissues and the development of in vitro models for studying lip-related cellular processes.

Recent Grants

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Identifying key elements of a p16INK4A/Laminin 5-dependent growth arrest/hypermotility response mechanism during epithelial development

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Grant: Close

Identifying key elements of a p16INK4A/Laminin 5-dependent growth arrest/hypermotility response mechanism during epithelial development

Open Date:

Close Date:

Grant: Close

Identifying key elements of a p16INK4A/Laminin 5-dependent growth arrest/hypermotility response mechanism during epithelial development

Open Date:

Close Date:

Articles (15)

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2025

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2025

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2025

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2025

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2024

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2024

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2024

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (2)

Stephan von Gunten

Associate Professor

University of Bern

SWITZERLAND

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Christos Katsaros

Professor and Chair

University of Bern

SWITZERLAND

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Martin Degen

Research Interests

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About

Recent Grants

Articles (15)

A volume-stable collagen matrix promotes osteogenesis and osteoinduction in cleft lip fibroblasts: A novel approach for alveolar cleft repair

The Skin-to-Mucosa Ratio Defines the Osteogenic Potential of Lip Fibroblasts

Selective modulation of the bone remodeling regulatory system through orthodontic tooth movement—a review

Epidemiologic trends of cleft lip and/or palate in Switzerland

Reflecting the human lip in vitro: Cleft lip skin and mucosa keratinocytes keep their identities

Immortalization of patient-derived lip cells for establishing 3D lip models

Cementum and enamel surface mimicry influences soft tissue cell behavior.

Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.

Consistent downregulation of the cleft lip/palate-associated genes <i>IRF6</i> and <i>GRHL3</i> in carcinomas.

Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes.

A Living Cell Repository of the Cranio-/Orofacial Region to Advance Research and Promote Personalized Medicine.

Tenascin-W Is a Novel Stromal Marker in Biliary Tract Cancers.

Tenascin-W: Discovery, Evolution, and Future Prospects.

Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.

A Novel Van der Woude Syndrome-Causing <i>IRF6</i> Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes.

Collaborators (2)

Stephan von Gunten

Christos Katsaros

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