Martin Grininger

Professor in Biomolecular Chemistry

Goethe University Frankfurt

Germany

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About

Martin Grininger is a Professor of Biomolecular Chemistry at Goethe University Frankfurt, Germany. His research primarily focuses on enzyme kinetics related to fatty acid synthesis and the role of acyl carrier proteins in biosynthetic pathways. Recent publications include studies on carbon-carbon bond formation in fatty acid synthase and the design principles imprinted by evolution, highlighting his contributions to the understanding of biochemical processes in metazoans.

Articles (19)

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2025

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2021

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2021

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2020

Collaborators (4)

Andreas Linden

University Medical Center Göttingen

GERMANY

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Zoya Ignatova

Professor in RNA Biochemistry

Universität Hamburg

GERMANY

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Sonja-Verena Albers

Professor

University of Freiburg

GERMANY

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David H. Sherman

Professort

University of Michigan

UNITED STATES

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Martin Grininger

Research Interests

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About

Articles (19)

Design principles imprinted by evolution

The enzyme kinetics of branched‐chain fatty acid synthesis of metazoan fatty acid synthase

Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases

Die Kinetik der Kohlenstoff‐Kohlenstoff‐Bindungsbildung in der metazoischen Fettsäure Synthase und ihr Einfluss auf die Produktgenauigkeit

The Kinetics of Carbon‐Carbon Bond Formation in Metazoan Fatty Acid Synthase and Its Impact on Product Fidelity

The malonyl/acetyl-transferase from murine fatty acid synthase is a promiscuous engineering tool for editing polyketide scaffolds

How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis

Wie Acyl‐Carrier‐Proteine (ACPs) die Biosynthese von Fettsäuren und Polyketiden steuern

Direct structural analysis of a single acyl carrier protein domain in fatty acid synthase from the fungus Saccharomyces cerevisiae

Docking Domain Engineering in a Modular Polyketide Synthase and Its Impact on Structure and Function

Enzymology of assembly line synthesis by modular polyketide synthases

Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast

Chemoenzymatic synthesis of fluorinated polyketides

Structural insights into the mechanism of archaellar rotational switching

Solution Structure and Conformational Flexibility of a Polyketide Synthase Module

Front Cover: Transacylation Kinetics in Fatty Acid and Polyketide Synthases and its Sensitivity to Point Mutations (ChemCatChem 12/2021)

Transacylation Kinetics in Fatty Acid and Polyketide Synthases and its Sensitivity to Point Mutations**

Correction: Engineering strategies for rational polyketide synthase design

Cell-Free Synthesis of Natural Compounds from Genomic DNA of Biosynthetic Gene Clusters

Collaborators (4)

Andreas Linden

Zoya Ignatova

Sonja-Verena Albers

David H. Sherman

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