Martin Götte

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Professor (venia legendi: Medical Biochemistry)

Westfälische Wilhelms Universität Münster Medizinische Fakultät

Germany

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Professor Martin Götte holds the venia legendi in Medical Biochemistry at Westfälische Wilhelms Universität Münster Medizinische Fakultät in Germany. His research interests include molecular pathways in breast and ovarian cancer, angiogenesis in cancer cells, and the role of glycosylation in aging and autoimmunity. He has authored several recent articles focusing on the prognostic value of signaling pathways and molecular markers in various gynecological conditions, including endometriosis.

Recent Grants

Grant: Open

CARES - Human ECM-based platform for anti-cancer drug testing

Open Date: 2023-11-01

Close Date: 2027-10-01

Grant: Close

Internationale wissenschaftliche Veranstaltung: „Gemeinschaftstagung der Deutschen Gesellschaft für Matrixbiologie und der Italienischen Gesellschaft für Bindegewebsforschung, Münster, 26.09.-29.09.2023“, Münster, 26.09.2023 - 29.09.2023

Open Date: 2023-09-01

Close Date: 2023-10-01

Grant: Open

HEPINIB - Heparanase inhibition as a multifunctional targeting approach in cancer

Open Date: 2023-01-01

Close Date: 2026-12-01

Grant: Close

TRENDO - Translational Research on Endometriosis

Open Date: 2021-12-01

Close Date: 2026-04-01

Grant: Close

The role of the heparan sulfate proteoglycan Syndecan-1 in radiation resistance of breast cancer.

Open Date: 2020-02-01

Close Date: 2023-01-01

Martin Götte

Research Interests

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Recent Grants

Articles (23)

Single-Cell mRNA Analysis for the Identification of Molecular Pathways of IRF1 in HER2+ Breast Cancer

The Prognostic Value of the Hedgehog Signaling Pathway in Ovarian Cancer

Role of syndecan-4 in angiogenesis and vasculogenic mimicry in triple negative breast cancer cells

Glycosylation Regulation by TMEM230 in Aging and Autoimmunity

Combined targeting of TCF7L1/2, PTEN, CDK6, and BCCIP by microRNA miR‐29c‐3p is associated with reduced invasion and proliferation of endometriotic cells

Decreased expression of Syndecan‐ 1 (CD138) in the endometrium of adenomyosis patients suggests a potential pathogenetic role

Carboxypeptidase Inhibitor LXN Expression in Endometrial Tissue Is Menstrual Cycle Phase-Dependent and Is Upregulated in Endometriotic Lesions

Assessment of the Ferroptosis Regulators: Glutathione Peroxidase 4, Acyl-Coenzyme A Synthetase Long-Chain Family Member 4, and Transferrin Receptor 1 in Patient-Derived Endometriosis Tissue

Endometriosis-Associated Ovarian Cancer: From Molecular Pathologies to Clinical Relevance

Transmembrane Protein TMEM230, Regulator of Glial Cell Vascular Mimicry and Endothelial Cell Angiogenesis in High-Grade Heterogeneous Infiltrating Gliomas and Glioblastoma

Expression of Reversion-Inducing Cysteine-Rich Protein with Kazal Motifs (<i>RECK</i>) Gene and Its Regulation by miR200b in Ovarian Endometriosis

Characterization of E-Cadherin, SSEA-1, MSI-1, and SOX-2 Expression and Their Association with Pale Cells in Adenomyosis.

miR-193b-5p and miR-374b-5p Are Aberrantly Expressed in Endometriosis and Suppress Endometrial Cell Migration In Vitro

Dysregulated Stem Cell Markers Musashi-1 and Musashi-2 are Associated with Therapy Resistance in Inflammatory Breast Cancer

Role of Syndecans in Ovarian Cancer: New Diagnostic and Prognostic Biomarkers and Potential Therapeutic Targets

SPOCK1 Overexpression Suggests Poor Prognosis of Ovarian Cancer

Neutrophil Extracellular Traps and Cancer: Trapping Our Attention with Their Involvement in Ovarian Cancer

The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor

The Tissue Factor Pathway in Cancer: Overview and Role of Heparan Sulfate Proteoglycans

Enzymatic Digestion of Cell-surface Heparan Sulfate Alters the Radiation Response in Triple-negative Breast Cancer Cells

The hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer

Role of syndecan-4 in breast cancer pathophysiology

The heparan sulphate proteoglycan Syndecan‐1 (CD138) regulates tumour progression in a 3D model of ductal carcinoma in situ of the breast

Collaborators (9)

Juan Gilabert-Estellés

Jacek Malejczyk

Sebastian Daniel Schäfer

Antonino Bruno

Sylvia mechsner

Nancy A Espinoza‐Sánchez

alberto passi

Paweł Włodarski

Philipp König

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