Martin McPhillie
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Lecturer
United KingdomResearch Interests
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About
Martin McPhillie is a Lecturer at the University of Leeds in the United Kingdom. His research primarily focuses on the design and characterization of novel therapeutic agents, with recent work on type II topoisomerase inhibitors, dual FLT3/TrKA inhibitors for acute myeloid leukemia, and Aurora B kinase inhibitors for breast cancer. Additionally, he investigates the structural implications of insulin and IGF1 receptors and explores novel allosteric binding regions in bacterial DNA gyrase to enhance antibacterial drug discovery.
Recent Grants
Grant: Close
Exploring novel binding pockets in DNA gyrase and DNA topoisomerase IV to address antibiotic resistance
Open Date: 2021-04-30
Close Date: 2024-04-29
Grant: Close
Exploiting the SARS-CoV-2 nsp14 3'-5'-exoribonuclease as a target for antiviral chemotherapy
Open Date: 2020-11-09
Close Date: 2021-11-08
Articles (10)
Year:
2022
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2022
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2022
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2021
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2021
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2021
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2020
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2020
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2020
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2020
Collaborators (6)
Kurt D. Ristroph
Purdue University
Stuart Woods
Academic, Lecturer, Lecturer
University of the West of Scotland OLD
Acely Garza-Garcia
The Francis Crick Institute
Craig Roberts
University Of Strathclyde
Colin Fishwick
Professor of Medicinal Chemistry
University of Leeds
Saverio Minucci
European Institute of Oncology
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