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Martine Therrien

Broad Institute

United States

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Research Interests

Biochemistry

10%

Neurology

20%

Glia

30%

Inflammatory Biology

20%

Huntington's Disease

10%

Genomic

10%

Dietary Science

10%

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Articles6

Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS

Article Link

Year:

2024

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.

Article Link

Year:

2023

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

Article Link

Year:

2023

Redefining microglia states: Lessons and limits of human and mouse models to study microglia states in neurodegenerative diseases.

Article Link

Year:

2022

Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.

Article Link

Year:

2020

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.

Article Link

Year:

2020

Collaborators3

Mathew Blurton-Jones

Professor

University of California, Irvine

UNITED STATES

Medina Colic

The University of Texas MD Anderson Cancer Center

UNITED STATES

Olli Pietilainen

University of Helsinki

FINLAND

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