Mathieu Vinken at Vrije Universiteit Brussel - Research Interests, Publications & Academic Profile

Mathieu Vinken

Vrije Universiteit Brussel

Belgium

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Research Interests

Biochemistry

50%

Pharmacology

70%

Fatty Liver

70%

Toxicology

60%

Metabolic Biology

40%

Pharmacogenomic

40%

Liver Fibrosis

30%

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Recent Grants

Grant: Close

An animal-free approach for human safety testing of food additives

Open Date: 2021-10-01

Close Date: 2022-09-01

Grant: Open

ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment

Open Date: 2021-05-01

Close Date: 2026-04-01

Grant: Open

Cellular communication as target and biomarker in liver disease and toxicity: from basic research towards clinical application

Open Date: 2021-01-01

Close Date: 2027-12-01

Grant: Close

Are connexins, pannexins and their (hemi)channels novel biomarkers and pharmacological targets in the prognosis and therapy of liver cancer?

Open Date: 2020-01-01

Close Date: 2023-12-01

Grant: Close

PANACHE: production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases

Open Date: 2019-12-01

Close Date: 2023-12-01

Articles18

Investigation of parenteral nutrition-induced hepatotoxicity using human liver spheroid co-cultures

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2024

Dataset on transcriptomic profiling of parenteral nutrition-induced hepatotoxicity in a human liver in vitro model

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2024

Parenteral nutrition-associated liver injury: clinical relevance and mechanistic insights

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2024

A quantitative weight-of-evidence method for confidence assessment of adverse outcome pathway networks: a case study on chemical-induced liver steatosis

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2024

E-waste: mechanisms of toxicity and safety testing

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2024

Hepatic cell junctions: Pulling a double‐duty

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2024

Accessible methods and tools to estimate chemical exposure in humans to support risk assessment: a systematic scoping review

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Year:

2024

Corrigendum to “Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support” [Biomed. Pharmacother. 174 (2024) 116530]

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2024

The application of natural language processing for the extraction of mechanistic information in toxicology

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2024

Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: analysis of a database of 432 patients developed by literature review and machine learning support

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2024

Pannexin1 channels in the liver: an open enemy.

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2023

Parenteral Nutrition, Sepsis, Acute Heart Failure and Hepatotoxic Drugs Are Related to Liver Test Disturbances in Critically Ill Patients

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2023

New Approach Methodologies in human regulatory toxicology – not if, but how and when!

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2023

Determination of structural features that underpin the pannexin1 channel inhibitory activity of the peptide 10Panx1

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2023

Unraveling the mechanisms underlying drug-induced cholestatic liver injury: identifying key genes using machine learning techniques on human in vitro data sets

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2023

Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma

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2023

Kupffer Cells Contested as Early Drivers in the Pathogenesis of Primary Sclerosing Cholangitis

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Year:

2023

Unraveling Hepatic Metabolomic Profiles and Morphological Outcomes in a Hybrid Model of NASH in Different Mouse Strains

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Year:

2023

Collaborators18

Xavier Verhelst

Associate Professor of Hepatology

Ghent University

BELGIUM

Anne Marie Vinggaard

Technical University of Denmark

DENMARK

Marth Stinckens

Vrije Universiteit Brussel

BELGIUM

Alexandra Gatzios

Vrije Universiteit Brussel

BELGIUM

Philip Marx-Stoelting

Scientific director/head of unit

Federal Institute for Risk Assessment (BfR)

GERMANY

Ellen Callewaert

Vrije Universiteit Brussel

BELGIUM

Raf Van Campenhout

Vrije Universiteit Brussel

BELGIUM

Hans Van Vlierberghe

Ghent University Hospital

BELGIUM

Zenzi Rosseel

Vrije Universiteit Brussel

BELGIUM

Milos Mihajlovic

Vrije Universiteit Brussel

BELGIUM

Tamara Vanhaecke

Vrije Universiteit Brussel

BELGIUM

Anouk Verhoeven

Vrije Universiteit Brussel

BELGIUM

Brenda Kwak

Full professor

University of Geneva

SWITZERLAND

Vera Rogiers

Vrije Universiteit Brussel

BELGIUM

Joop Jonckheer

Vrije Universiteit Brussel

BELGIUM

Anne Caufriez

Vrije Universiteit Brussel

BELGIUM

Hendrik Reynaert

Vrije Universiteit Brussel

BELGIUM

Andres Tabernilla

Vrije Universiteit Brussel

BELGIUM

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