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Matthew Holt

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ERA NET Chair for Neurobiology

Instituto de Investigação e Inovação em Saúde da Universidade do Porto

Portugal

Research Interests

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Professors in Portugal

Recent Grants

Grant: Open

Tripartite synapses in neurodevelopmental disorders

Open Date: 2025-12-22

Close Date: 2028-12-21

Grant: Close

Training within the research program in Neurobiology and Neurological Diseases - support for the ERA Chair NCBio

Open Date: 2024-10-01

Close Date:

Grant: Close

Confronting dementia in the front line: the role of astrocytes

Open Date: 2022-01-01

Close Date: 2022-01-01

Grant: Close

Astrocyte dysfunctions in Phelan-McDermid syndrome: from mechanisms towards new therapeutic strategies

Open Date: 2022-01-01

Close Date: 2025-01-01

Grant: Close

Investigating the role of astrocytes and noradrenaline as critical regulators of neuronal circuit excitability

Open Date: 2022-01-01

Close Date: 2025-01-01

Articles (16)

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2022

Collaborators (12)

Mykhailo Y. Batiuk

EPFL (École Polytechnique Fédérale de Lausanne)

SWITZERLAND

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Francisco Pestana

KU Leuven Institute for Single Cell Omics (LISCO)

BELGIUM

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Hiroshi Kawasaki

Professor

Kanazawa University Graduate School of Medical Sciences

JAPAN

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Inbal Goshen

Hebrew University of Jerusalem

ISRAEL

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Axel Nimmerjahn

Professor

Salk Institute for Biological Studies

UNITED STATES

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Chris Dulla

Tufts University School of Medicine

UNITED STATES

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João Filipe Oliveira

Principal Investigator

University of Minho

PORTUGAL

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Corrado Calì

Associate Professor

University of Turin

ITALY

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Maxime Vande Vyver

Vrije Universiteit Brussel

BELGIUM

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Ruth Beckervordersandforth

Heisenbergprofessor

Friedrich Alexander Universität Erlangen Nürnberg Medizinische Fakultät

GERMANY

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Benedikt Sebastian Nilges

Head of Science and Technology

OMAPiX GmbH

GERMANY

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James Dooley

Research Professor

University of Cambridge

UNITED KINGDOM

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ApplyKite TwinLearns as you apply

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Matthew Holt

Research Interests

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Recent Grants

Articles (16)

The multiple scales of astrocytic functional units

Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States

Astrocytes and the ageing synapse

Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity

Retro-Orbital Delivery of AAVs for CNS Wide Astrocyte Targeting

Regulatory T cells as a possible new target in epilepsy?

Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice

Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution

Association of Serum Biomarkers With Neurocognitive Decline After PCI in Small Cell Lung Cancer: An Exploratory Study of the Phase III NCT01780675 Trial

The astrocyte α1A‐adrenoreceptor is a key component of the neuromodulatory system in mouse visual cortex

Studying the Role of Astrocytes at Synapses Using Single-Cell Transcriptomics

Astrocyte structural heterogeneity in the mouse hippocampus

Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain

Chemogenetic manipulation of astrocyte activity at the synapse— a gateway to manage brain disease

Astrocyte heterogeneity and interactions with local neural circuits

A new technical approach for cross-species examination of neuronal wiring and adult neuron-glia functions.

Collaborators (12)

Mykhailo Y. Batiuk

Francisco Pestana

Hiroshi Kawasaki

Inbal Goshen

Axel Nimmerjahn

Chris Dulla

João Filipe Oliveira

Corrado Calì

Maxime Vande Vyver

Ruth Beckervordersandforth

Benedikt Sebastian Nilges

James Dooley

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