Matthew Philip Crump

University of Bristol

United Kingdom

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Articles (22)

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2025

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2025

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2025

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2025

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2025

Integrating total synthesis with genetic engineering of Sorangium strains reveal insights into the enzyme-catalysed formation of the 20,21-alkene in ambruticin biosynthesis.

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

Collaborators (25)

Mark Dodding

University of Bristol

UNITED KINGDOM

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Christopher Williams

University of Bristol

UNITED KINGDOM

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Dominic Campopiano

Professor

UNITED KINGDOM

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John Crosby

Academic , Associate Professor

University of Bristol

UNITED KINGDOM

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Derek Woolfson

University of Bristol

UNITED KINGDOM

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Guto Rhys

Lecturer (Asst. Prof) in Biological Chemistry

Cardiff University

UNITED KINGDOM

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Richard Sessions

University of Bristol

UNITED KINGDOM

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Andy Bailey

University of Bristol

UNITED KINGDOM

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Marc van der Kamp

Professor

University of Bristol

UNITED KINGDOM

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Rob Barringer

University of Bristol

UNITED KINGDOM

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Tom Oliver

University of Bristol

UNITED KINGDOM

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Johannes Weijman

University of Otago

NEW ZEALAND

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Ross Anderson

University of Bristol

UNITED KINGDOM

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James Bowen

University of Bristol

UNITED KINGDOM

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Christine L. Willis

University of Bristol

UNITED KINGDOM

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Paul R. Race

University of Bristol

UNITED KINGDOM

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Sbusisiwe Mbatha

Professional and Administrative, Centre Manager - QETLabs

University of Bristol

UNITED KINGDOM

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Adrian Mulholland

Professor at School of Physics

University of Bristol

UNITED KINGDOM

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Jody Mason

Professor of Biochemistry

University of Bath

UNITED KINGDOM

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Chris Williams

Academic , Senior Lecturer

University of Bristol

UNITED KINGDOM

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Ana Sofia Fernandes Oliveira

University of Bristol

UNITED KINGDOM

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Edmund R. R. Moody

University of Bristol

UNITED KINGDOM

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Roberto A. Steiner

King’s College London

UNITED KINGDOM

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Katherine Williams

University of Bristol

UNITED KINGDOM

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Stefano Artin Serapian

University of Bristol

UNITED KINGDOM

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Matthew Philip Crump

Research Interests

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Articles (22)

Divergent Tandem Acyl Carrier Proteins Necessitate In‐Series Polyketide Processing in the Leinamycin Family

Divergent Tandem Acyl Carrier Proteins Necessitate In‐Series Polyketide Processing in the Leinamycin Family

In vivo and in vitro investigations provide insights into maleidride biosynthesis in fungi

Stabilizing a Native Fold of Alpha-Synuclein with Short Helix-Constrained Peptides

Genetic engineering of Sorangium cellulosum reveals hidden enzymology in myxobacterial natural product biosynthesis

Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis

Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis

An Integrated Module Performs Selective ‘Online’ Epoxidation in the Biosynthesis of the Antibiotic Mupirocin

An expandable, modular de novo protein platform for precision redox engineering

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis

An N-terminal alpha-synuclein fragment binds lipid vesicles to modulate lipid-induced aggregation

X-ray structure of the metastable SEPT14–SEPT7 coiled coil reveals a hendecad region crucial for heterodimerization

Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase

Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis.

Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin

Path to Actinorhodin: Regio- and Stereoselective Ketone Reduction by a Type II Polyketide Ketoreductase Revealed in Atomistic Detail

Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans

The structural basis for high affinity binding of α1-acid glycoprotein to the potent antitumor compound UCN-01

Molecular mechanism for kinesin-1 direct membrane recognition

Structural resolution of switchable states of a de novo peptide assembly

Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis

Collaborators (25)

Mark Dodding

Christopher Williams

Dominic Campopiano

John Crosby

Derek Woolfson

Guto Rhys

Richard Sessions

Andy Bailey

Marc van der Kamp

Rob Barringer

Tom Oliver

Johannes Weijman

Ross Anderson

James Bowen

Christine L. Willis

Paul R. Race

Sbusisiwe Mbatha

Adrian Mulholland

Jody Mason

Chris Williams

Ana Sofia Fernandes Oliveira

Edmund R. R. Moody

Roberto A. Steiner

Katherine Williams

Stefano Artin Serapian

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