Matthew Witkowski

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Assistant Professor

University of Colorado Boulder

United States

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About

Matthew Witkowski is an Assistant Professor at the University of Colorado, USA. His research focuses on the molecular mechanisms underlying acute lymphoblastic leukemia, particularly in T-cell and B-cell pathogenesis. He has authored articles on topics such as the clonal evolution of chromatin landscapes in leukemia and the role of immune control in acute myeloid leukemia.

Recent Grants

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Boettcher Investigator Award

Open Date: 2023-06-01

Close Date: 2026-06-01

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Modeling relapsed hypodiploid B-cell acute lymphoblastic leukemia using humanized in vivo systems

Open Date: 2023-01-01

Close Date: 2024-12-01

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RNA-binding protein, NUDT21, enhances CD19 abundance on human B-cell acute lymphoblastic leukemia cells.

Open Date: 2022-07-01

Close Date: 2023-06-01

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Dissecting the Functional Role of Monocytes in B-cell Acute Lymphoblastic Leukemia Survival

Open Date: 2022-05-01

Close Date: 2025-04-01

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ASH Restart Award

Open Date: 2020-11-01

Close Date: 2021-11-01

Articles (13)

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2022

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2022

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2022

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2020

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2020

Collaborators (16)

Palaniraja Thandapani

Assistant Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

Matthew Witkowski

Research Interests

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About

Recent Grants

Articles (13)

Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia

Clonal evolution of the 3D chromatin landscape in patients with relapsed pediatric B-cell acute lymphoblastic leukemia

Concepts in B cell acute lymphoblastic leukemia pathogenesis

Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Oncogenic drivers dictate immune control of acute myeloid leukemia.

Flow cytometric assessment of leukemia-associated monocytes in childhood B-cell acute lymphoblastic leukemia outcome.

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion.

Single-cell analysis of acute lymphoblastic and lineage-ambiguous leukemia: approaches and molecular insights

An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia.

Valine tRNA levels and availability regulate complex I assembly in leukaemia

Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia

Leukemia-on-a-chip: Dissecting the chemoresistance mechanisms in B cell acute lymphoblastic leukemia bone marrow niche

Collaborators (16)

Palaniraja Thandapani

Anastasia Tikhonova

Bettina Nadorp

Sarah LeBoeuf

Valeria Mezzano

Xufeng Chen

Claudia Bruedigam

Eric Wang

Fernando Souza‐Fonseca‐Guimaraes

Justin Eyquem

Igor Dolgalev

Zhaohui Wang

Maarten Fornerod

Christina Glytsou

Timothee Lionnet

Gloria Paz Contreras Yametti

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