Matthias Arnold

Has grant

Adj. Associate Professor

Duke University

United States

Research Interests

Explore related searches

Professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Matthias Arnold is an Adjunct Associate Professor at Duke University in the United States. His research focuses on neurodegenerative diseases, particularly Alzheimer's disease, as well as the bioenergetic mechanisms related to mental health conditions such as depression. Recent articles authored by Professor Arnold explore the influence of APOE genotype on brain metabolism, the lipidomic profiles associated with Alzheimer's disease, and the impacts of dietary interventions on metabolic health. He is also involved in studies addressing the broad effects of peripheral inflammation and multimorbidity in cognitive decline and severe COVID-19.

Recent Grants

Grant: Close

TargetAD: A systems multi-omics approach to drug repositioning in Alzheimer's disease

Open Date: 2021-09-01

Close Date: 2026-05-31

Grant: Close

Alzheimer's Gut Microbiome Project

Open Date: 2019-09-15

Close Date: 2024-08-31

Grant: Close

Metabolomic Signatures for Disease Sub-classification and Target Prioritization in AMP-AD

Open Date: 2018-09-30

Close Date: 2023-08-31

Grant: Close

Gut Liver Brain Biochemical Axis in Alzheimer's Disease

Open Date: 2018-08-15

Close Date: 2023-06-30

Grant: Close

Metabolic Networks and Pathways Predictive of Sex Differences in AD Risk and Responsiveness to Treatment

Open Date: 2018-08-01

Close Date: 2023-06-30

Articles (26)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Collaborators (24)

Augustus Rush

Adjunct Professor

Texas Tech University

UNITED STATES

Matthias Arnold

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (26)

Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort

APOE genotype influences on the brain metabolome of aging mice - role for mitochondrial energetics in mechanisms of resilience in APOE2 genotype.

Trajectory of plasma lipidome associated with the risk of late-onset Alzheimer's disease: a longitudinal cohort study

Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease

Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer’s disease in humans

The metabolome-wide signature of major depressive disorder

Complex patterns of multimorbidity associated with severe COVID-19 and long COVID

The HuMet Repository: Watching human metabolism at work

Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer’s disease

Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease

Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease

New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop

Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer's disease and progressive supranuclear palsy

Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals

Serum Bile Acids Improve Prediction of Alzheimer's Progression in a Sex‐Dependent Manner

Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data

Plasma proteomic associations with genetics and health in the UK Biobank

Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease

APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species

Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease

Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations

The landscape of metabolic brain alterations in Alzheimer's disease

Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression

Metabolomic and Inflammatory Signatures of Symptom Dimensions in Major Depression

Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification

Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease

Collaborators (24)

Augustus Rush

Marco Fernandes

Ian James Martins

Anubha Mahajan

Rebecca Baillie

Ralph Martins

Harry Hemingway

Jesse Wiley

Boadie Dunlop

Alejo Nevado-Holgado

Mandakh Bekhbat

Rick Jansen

Nina McCarthy

Maik Pietzner

Andrew Saykin

Michael Inouye

Alysha De Livera

Eric Moses

Taeho Jo

Peter Meikle

Pratishtha Chatterjee

Jennifer S. Labus

John Beilby

dinesh barupal

Make your next move.