Matthias P. Wymann

University of Basel

Switzerland

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Articles (10)

Year:

2022

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2022

Year:

2021

Year:

2021

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2021

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (7)

Erhan Keles

EPFL (École Polytechnique Fédérale de Lausanne)

SWITZERLAND

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Chiara Borsari

L'Oréal-UNESCO Fellow and Adjunct Professor

University of Milan

ITALY

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Thorsten Schaefer

University Lecturer in Chemistry & Biochemistry

University of Basel

SWITZERLAND

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Mayumi Mori

Senior Lecturer (Endowed)

Kyoto University

JAPAN

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Carrie L. Lucas

Yale University School of Medicine

UNITED STATES

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Wojciech Bal

Professor

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Jean Pieters

Professor of Biochemistry

Universität Basel Department Biozentrum

SWITZERLAND

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Matthias P. Wymann

Research Interests

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Articles (10)

Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα

The role of PI3Kγ in the immune system: new insights and translational implications

Targeting Phosphoinositide 3-Kinase – Five Decades of Chemical Space Exploration

Chemical and Structural Strategies to Selectively Target mTOR Kinase

Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors

Suppression of caspase 8 activity by a coronin 1–PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling

Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood–brain barrier permeability

Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood-brain barrier permeability.

PI3K<i>γ</i> Regulatory Protein p84 Determines Mast Cell Sensitivity to Ras Inhibition-Moving Towards Cell Specific PI3K Targeting?

Brain-penetrant PQR620 mTOR and PQR530 PI3K/mTOR inhibitor reduce huntingtin levels in cell models of HD

Collaborators (7)

Erhan Keles

Chiara Borsari

Thorsten Schaefer

Mayumi Mori

Carrie L. Lucas

Wojciech Bal

Jean Pieters

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