MATTIA FALCONI

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Università degli Studi di Roma La Sapienza

Italy

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About

Mattia Falconi is an Associate Professor at Università degli Studi di Roma Tor Vergata, Italy. His research encompasses various areas, including structural modeling of protein complexes, antifungal agents, and antimicrobial activities of natural compounds. Recent articles highlight his work on the mechanisms of action of topoisomerase inhibitors and the phylogeography of loggerhead turtles, contributing insights into both biological and clinical perspectives.

Recent Grants

Grant: Close

DNA VAULT - Simulation of a DNA origami nanostructure able to control single molecule enzymatic activity

Open Date: 2017-04-01

Close Date: 2018-04-01

Grant: Close

NANOCARGO - Design of self-assembling DNA nano-cages provided with pH and temperature controlled gates for the target delivery of biomolecules.

Open Date: 2015-03-01

Close Date: 2016-03-01

Grant: Close

DNANANO - Molecular dynamics simulation and experimental characterization of a DNA nanocage family.

Open Date: 2012-03-01

Close Date: 2013-03-01

Articles (18)

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Paolo Visca

Full Professor of Microbiology

Roma Tre University

ITALY

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FRANCESCA PICA

Associate Professor of Microbiology

Università degli Studi di Roma Tor Vergata Facoltà di Medicina e Chirurgia

ITALY

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ITALY

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Emi Dika

ITALY

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Roberta Gaziano

Associate Professor

University of Rome Tor Vergata

ITALY

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Carolina Scagnolari

ITALY

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MATTIA FALCONI

Research Interests

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About

Recent Grants

Articles (18)

Retinoids as Alternative Antifungal Agents Against Candida albicans: In Vitro and In Silico Evidence

In Silico Structural Modeling of the HuR-mRNA Complex: Insights into Structural and Functional Regulation

Unveiling the Mechanism of Action of Palmitic Acid, a Human Topoisomerase 1B Inhibitor from the Antarctic Sponge <i>Artemisina plumosa</i>

Deciphering the Role of Trehalose in Chroococcidiopsis sp. 029’s High-Desiccation Resistance: Sequence Determination, Structural Modelling and Simulative Analysis of the 30S Ribosomal Subunit

Pharmacological inhibition of PDGF-C/neuropilin-1 interaction: A novel strategy to reduce melanoma metastatic potential

Whole mitochondrial genome sequencing provides new insights into the phylogeography of loggerhead turtles (Caretta caretta) in the Mediterranean Sea

Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis

Deciphering the Broad Antimicrobial Activity of Melaleuca alternifolia Tea Tree Oil by Combining Experimental and Computational Investigations

From In Silico Simulation between TGF-<i>β</i> Receptors and Quercetin to Clinical Insight of a Medical Device Containing <i>Allium cepa</i>: Its Efficacy and Tolerability on Post-Surgical Scars

Experimental and in silico evaluations of the possible molecular interaction between airborne particulate matter and SARS-CoV-2.

Computational and experimental validation of phthalocyanine and hypericin as effective SARS-CoV-2 fusion inhibitors.

Preliminary Evidence of Efficacy, Safety, and Treatment Satisfaction with Tirbanibulin 1% Ointment: A Clinical Perspective on Actinic Keratoses

Lactoferrin Binding to SARS-CoV-2 Spike Glycoprotein Blocks Pseudoviral Entry and Relieves Iron Protein Dysregulation in Several In Vitro Models

Dimethylmyricacene: An In Vitro and In Silico Study of a Semisynthetic Non-Camptothecin Derivative Compound, Targeting Human DNA Topoisomerase 1B

Editorial: Interaction of Biomolecules and Bioactive Compounds With the SARS-CoV-2 Proteins: Molecular Simulations for the Fight Against Covid-19

Potential Use of Tea Tree Oil as a Disinfectant Agent against Coronaviruses: A Combined Experimental and Simulation Study

Interaction of <i>Pelargonium sidoides</i> Compounds with Lactoferrin and SARS-CoV-2: Insights from Molecular Simulations

Lactoferrin as Antiviral Treatment in COVID-19 Management: Preliminary Evidence

Collaborators (14)

Andrea Battistoni

ANTIMO CUTONE

Silvia Biocca

Jim Olds

Luca Bianchi

Paolo Visca

FRANCESCA PICA

Luigi Rosa

Maria Carmela Bonaccorsi di Patti

alessandro desideri

Daniela Billi

Emi Dika

Roberta Gaziano

Carolina Scagnolari

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