Maud Gratuze

Aix-Marseille University

France

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Articles (11)

Year:

2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (6)

Frédéric Calon

Professeur titulaire

Laval University

CANADA

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Samira Parhizkar

Washington University in St. Louis

UNITED STATES

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Michael Strickland

Washington University in St. Louis

UNITED STATES

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Eric Landsness

Assistant Professor

Washington University

UNITED STATES

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David M. Holtzman

Washington University School of Medicine

UNITED STATES

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Oleg Butovsky

Associate Professor of Neurology

Brigham and Women's Hospital

UNITED STATES

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Maud Gratuze

Research Interests

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Articles (11)

Age-dependent impact of streptozotocin on metabolic endpoints and Alzheimer's disease pathologies in 3xTg-AD mice.

Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a <i>TREM2</i>-dependent manner in mice.

Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration.

Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy.

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.

APOE antibody inhibits Aβ‐associated tau seeding and spreading in a mouse model

Activated microglia mitigate aβ-associated tau seeding and spreading

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

Targeting pre-synaptic tau accumulation: a new strategy to counteract tau-mediated synaptic loss and memory deficits.

APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.

Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration.

Collaborators (6)

Frédéric Calon

Samira Parhizkar

Michael Strickland

Eric Landsness

David M. Holtzman

Oleg Butovsky

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