Max Nobis

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Head

UCL Cancer Institute

Belgium

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About

Dr. Max Nobis is the Head at the VIB-KU Leuven Center for Cancer Biology in Belgium. His research focuses on cancer biology, neuromuscular diseases, and therapeutic responses, as evidenced by his recent publications on topics such as the role of aspartate signaling in lung metastasis and the impact of pharmacologic inhibition in Duchenne Muscular Dystrophy. His work also explores cellular mechanisms in confined environments and strategies to improve cancer treatment outcomes.

Recent Grants

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Intravital imaging using AKT and DNA damage biosensor mice for drug target validation to improve PARP and PI3K inhibition in pancreatic cancer

Open Date: 2018-01-01

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Cdk4/6 and Cdk1 inhibition in breast cancer: intravital insights to overcome Cdk4/6 Palbociclib resistance in vivo using Cdk1-FRET biosensor mice technology

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Articles (10)

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2025

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2023

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2023

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2023

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2023

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2023

Collaborators (18)

Ruslan Dmitriev

Assistant Professor

Ghent University

BELGIUM

Max Nobis

Research Interests

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About

Recent Grants

Articles (10)

Pharmacologic Inhibition of Glutamate Dehydrogenase 1 Improves Functional Recovery of Neuromuscular Junctions and Muscle Function in Duchenne Muscular Dystrophy

Aspartate signalling drives lung metastasis via alternative translation

Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.

Compression-dependent microtubule reinforcement enables cells to navigate confined environments

Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients

Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma.

Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse

Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC

A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer

BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis

Collaborators (18)

Ruslan Dmitriev

Nikolas Haass

Sergey M. Borisov

Dietmar Oelz

Sean Warren

Neil Merrett

Ginevra Doglioni

Paul Timpson

Joanna Achinger-Kawecka

Alistair Forrest

Kevin Dean

Alvin Kamili

Lorraine Chantrill

Mark A Febbraio

Peter Meikle

Thomas Cox

Eric Fey

Brooke Pereira

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