Megan Griffiths

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Assistant Professor

University of Texas Southwestern Department of Pediatrics

United States

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Megan Griffiths is an Assistant Professor at The University of Texas Southwestern Medical Center in the Department of Pediatrics. Her research focuses on pediatric pulmonary hypertension, particularly in areas such as drug development, biomarker identification, and the relationship between metabolic pathways and disease severity. Recent publications include studies on the predictive value of resistin and insulin-like growth factors in pulmonary arterial hypertension.

Recent Grants

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Pediatric Scientist Development Program (K12) 2017-2022

Open Date: 1986-12-01

Close Date: 2022-06-30

Articles (15)

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2025

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2021

Collaborators (4)

Raul Chavez-Valdez

Associate Professor

Johns Hopkins University

UNITED STATES

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Melania M. Bembea

UNITED STATES

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Eric D. Austin

Vanderbilt University Medical Center

UNITED STATES

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Catherine Simpson

Johns Hopkins University

UNITED STATES

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Megan Griffiths

Research Interests

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Recent Grants

Articles (15)

Enhancing Drug Development for Paediatric Pulmonary Hypertension—An Integrative Perspective

Multiple biomarkers are equivalent to clinical pulmonary arterial hypertension survival risk models

Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension.

Low‐affinity insulin‐like growth factor binding protein 7 and its association with pulmonary arterial hypertension severity and survival

Intravenous prostacyclins for right ventricular failure following left ventricular assist device in paediatric heart failure.

Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival.

Cardiac Dysfunction Biomarkers Are Associated With Potential for Successful Separation From Extracorporeal Membrane Oxygenation in Children

Metabolomic Differences in Connective Tissue Disease-Associated Versus Idiopathic Pulmonary Arterial Hypertension in the PVDOMICS Cohort.

Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension.

Perinatal Inflammatory Biomarkers and Respiratory Disease in Preterm Infants.

Cardiac Dysfunction Biomarkers are Associated with Potential for Successful Separation from Extracorporeal Membrane Oxygenation in Children.

Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity.

<i>COL18A1</i> genotypic associations with endostatin levels and clinical features in pulmonary arterial hypertension: a quantitative trait association study.

Hepatoma-derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival.

Angiostatic Peptide, Endostatin, Predicts Severity in Pediatric Congenital Heart Disease–Associated Pulmonary Hypertension

Collaborators (4)

Raul Chavez-Valdez

Melania M. Bembea

Eric D. Austin

Catherine Simpson

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