Megan McClean

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Associate Professor

University of Wisconsin-Madison

United States

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Megan McClean is an Associate Professor at the University of Wisconsin-Madison in the United States. Her research focuses on optogenetics, yeast biology, and cellular signaling, with recent investigations into transcription factor dynamics and GTP synthesis regulation. She has contributed to innovative methodologies for high-throughput optogenetic experiments and the analysis of dynamic cellular processes.

Recent Grants

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Career Award at the Scientific Interface

Open Date: 2015-01-01

Close Date: 2021-01-01

Articles (15)

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2020

Collaborators (1)

Ophelia Venturelli

Assistant Professor

University of Wisconsin-Madison

UNITED STATES

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Megan McClean

Research Interests

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Recent Grants

Articles (15)

Dynamic Multiplexed Control and Modeling of Optogenetic Systems Using the High-Throughput Optogenetic Platform, Lustro

Protocol to probe how promoters decode TF dynamics in Saccharomyces cerevisiae by combining optogenetic control with microscopy

Live-cell analysis of IMPDH protein levels during yeast colony growth provides insights into the regulation of GTP synthesis

Tuning interdomain conjugation to enable in situ population modification in yeasts

Lustro: High-Throughput Optogenetic Experiments Enabled by Automation and a Yeast Optogenetic Toolkit

Transcription factor localization dynamics and DNA binding drive distinct promoter interpretations

Strain‐dependent differences in coordination of yeast signalling networks

Correction to “Lustro: High-Throughput Optogenetic Experiments Enabled by Automation and a Yeast Optogenetic Toolkit”

Cellular context alters EGF-induced ERK dynamics and reveals potential crosstalk with GDF-15

Give and take in the exometabolome

Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway

Optogenetic Tools for Control of Public Goods in Saccharomyces cerevisiae

Automated calibration of optoPlate LEDs to reduce light dose variation in optogenetic experiments

Under oil open-channel microfluidics empowered by exclusive liquid repellency

A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae

Collaborators (1)

Ophelia Venturelli

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