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Megan Radyk

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Assistant Professor of Oncology

Roswell Park Comprehensive Cancer Center

United States

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Recent Grants

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Metabolic regulation of pancreatic metaplasia and neoplasia

Open Date: 2024-09-06

Close Date: 2026-08-31

Grant: Close

Metabolic pathways regulate metaplasia and cancer initiation in the pancreas

Open Date: 2023-04-01

Close Date: 2024-03-31

Grant: Close

Stress Pathways in the Induction of Metaplasia

Open Date: 2018-12-01

Close Date: 2021-11-30

Articles (16)

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Collaborators (12)

Cyrus Sarosh

University of Michigan–Ann Arbor

UNITED STATES

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Jeffrey Brown

Assistant Professor - Molecular Cell Biology

Washington University in Saint Louis School of Medicine

UNITED STATES

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Celine L. St Pierre

Washington University School of Medicine

UNITED STATES

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Jiaqi Shi

Associate Professor

University of Michigan

UNITED STATES

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Miguel Quiros

University of Michigan

UNITED STATES

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W. Nathaniel Brennen

Associate Professor

Johns Hopkins University School of Medicine

UNITED STATES

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Anguraj Sadanandam

Professor of Data Science and Translational Oncology

Institute of Cancer Research

UNITED KINGDOM

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Yu Ming

Fred Hutchinson Cancer Research Center

UNITED STATES

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Timothy Frankel

Assistant Professor

University of Michigan Hospital

UNITED STATES

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Huy Dinh

Assistant Professor

University of Wisconsin-Madison

UNITED STATES

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Jason Mills

Chair and professor

Penn State College of Medicine

UNITED STATES

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Sarah Glass

Research Assistant Professor

UPMC Hillman Cancer Center

UNITED STATES

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Megan Radyk

Research Interests

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Recent Grants

Articles (16)

NADPH-producing enzymes restrict the formation of pancreatic precancerous lesions

Cathartocytosis: Jettisoning of cellular material during reprogramming of differentiated cells

ERMCS induction drives ADM in ex vivo models

NADPH-producing enzymes restrict precancer progression in the pancreas

Metabolic landscape of the healthy pancreas and pancreatic tumor microenvironment

The Hallmarks of Precancer

Dietary Iron Is Necessary to Support Proliferative Regeneration after Intestinal Injury

Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome

Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions

Cathartocytosis: How Cells Jettison Unwanted Material as They Reprogram

Uridine- to-ribose axis supports glucose-restricted pancreatic cancer

Uridine-derived ribose fuels glucose-restricted pancreatic cancer

Evaluation of an 8-week high school science communication course designed to read, write, and present scientific research

Defining the role of endoplasmic reticulum in the initiation of paligenosis

Glucose-6-phosphate dehydrogenase deficiency accelerates pancreatic acinar-to-ductal metaplasia

Collaborators (12)

Cyrus Sarosh

Jeffrey Brown

Celine L. St Pierre

Jiaqi Shi

Miguel Quiros

W. Nathaniel Brennen

Anguraj Sadanandam

Yu Ming

Timothy Frankel

Huy Dinh

Jason Mills

Sarah Glass

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