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Melanie Königshoff

Professor of Medicine

University of Pittsburgh

United States

Research Interests

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Articles (20)

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2026

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2024

Collaborators (13)

Hani N Alsafadi

Lund University

SWEDEN

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Peter Chen

Director, Division of Pulmonary and Critical Care Medicine

Cedars-Sinai Medical Center

UNITED STATES

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Mareike Lehmann

Professor of Translational Inflammation Research

Philipps-Universität Marburg

GERMANY

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Timothy Dye

Professor and Chair

Florida Atlantic University

UNITED STATES

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Carolyn Glass

Duke University

UNITED STATES

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Jerry Krishnan

University of Illinois Chicago (UIC)

UNITED STATES

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Kambez Hajipouran Benam

University of Pittsburgh

UNITED STATES

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Claudia Staab-Weijnitz

Associate Professor

University of Colorado Anschutz Medical Campus

UNITED STATES

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Paul Robson

Professor

Jackson Laboratory - Farmington

UNITED STATES

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Nicholas Kenyon

Program Director, UC Davis StARR Training Program in Veterinary and Human Health

University of California, Davis

UNITED STATES

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Siyuan (Steven) Wang

Associate Professor

Yale University

UNITED STATES

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Robert Wise

Professor

Johns Hopkins University

UNITED STATES

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Darcy Wagner

Professor

Lund University

SWEDEN

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Melanie Königshoff

Research Interests

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Articles (20)

Hallmarks of the ageing lung: 10 years later

Evaluation of statistical differential analysis methods for identification of senescent cells using single-cell transcriptomics

Turning the tide on organ fibrosis: a special issue on scientific advances and next-generation treatments

Fueling the fire: metabolic dysfunction and senescence as drivers of lung aging and disease

SenSet defines cell-type specific senescence signatures in the aged human lung

Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models

Advancing biological understanding of cellular senescence with computational multiomics

Post-COPD: Can Emphysema Be Repaired?

A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases

Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease An Official American Thoracic Society Research Statement

Approach to the Evaluation and Management of Interstitial Lung Abnormalities An Official American Thoracic Society Clinical Statement

Distinct Senescence-associated Secretory Phenotype Mediators Associate With an Aging Endotype and Multiorgan Dysfunction in COPD

Macrophage C1q contributes to pulmonary fibrosis by disturbing the metabolism of alveolar epithelial cells

Precision-Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research: An Official American Thoracic Society Workshop Report

Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena: An Official American Thoracic Society Report.

Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis

Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD

Teatime: epigallocatechin gallate targets fibroblast–epithelial cell crosstalk to combat lung fibrosis

Airway-derived emphysema-specific alveolar type II cells exhibit impaired regenerative potential in COPD

Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis

Collaborators (13)

Hani N Alsafadi

Peter Chen

Mareike Lehmann

Timothy Dye

Carolyn Glass

Jerry Krishnan

Kambez Hajipouran Benam

Claudia Staab-Weijnitz

Paul Robson

Nicholas Kenyon

Siyuan (Steven) Wang

Robert Wise

Darcy Wagner

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