Melanie Ruffner

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Assistant Professor

University of Pennsylvania

United States

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Recent Grants

Grant: Close

Epigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitis

Open Date: 2020-01-01

Close Date: 2024-12-31

Grant: Close

IL-4 Overexpressing Dendritic Cells and Exosomes for Treatment of Type 1 Diabetes

Open Date: 2008-09-01

Close Date: 2011-05-31

Grant: Close

IL-4 Overexpressing Dendritic Cells and Exosomes for Treatment of Type 1 Diabetes

Open Date: 2008-09-01

Close Date: 2011-05-31

Articles (11)

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (3)

Juan Abonia

Professor

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Jonathan Spergel

Professor

Children's Hospital of Philadelphia

UNITED STATES

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Michael Gluck

Gastroenterologist, Clinical Programs Development, Former Chief of Medicine

UNITED STATES

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Melanie Ruffner

Research Interests

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Recent Grants

Articles (11)

Persistent esophageal changes after histologic remission in eosinophilic esophagitis

International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.

CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis.

Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use.

Effect of topical swallowed steroids on the bacterial and fungal esophageal microbiota in eosinophilic esophagitis

Medical Management of Eosinophilic Esophagitis in Pediatric Patients.

CON: Peripheral intravenous access should always be secured before initiating food protein-induced enterocolitis syndrome oral food challenge.

Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis

RNA sequencing identifies global transcriptional changes in peripheral CD4+ cells during active oesophagitis and following epicutaneous immunotherapy in eosinophilic oesophagitis

Type 2 Immunity and Age Modify Gene Expression of COVID19 Receptors in Eosinophilic Gastrointestinal Disorders.

The role of eosinophils in immunotherapy.

Collaborators (3)

Juan Abonia

Jonathan Spergel

Michael Gluck

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