Melissa McGovern

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Baylor College of Medicine

United States

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Understanding the mechanism of Sox2 haploinsufficiency on supporting cell to hair cell conversion in the mature mouse cochlea.

Open Date: 2020-07-01

Close Date: 2022-06-30

Articles (6)

Year:

2024

Year:

2024

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Collaborators (3)

Tanner Monroe

Northwestern University Feinberg School of Medicine

UNITED STATES

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Chenghang Zong

Baylor College of Medicine

UNITED STATES

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Andrew K. Groves

UNITED STATES

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Melissa McGovern

Research Interests

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Recent Grants

Articles (6)

Expression of Atoh1 , Gfi1 , and Pou4f3 in the mature cochlea reprograms nonsensory cells into hair cells

Reprogramming with Atoh1, Gfi1, and Pou4f3 promotes hair cell regeneration in the adult organ of Corti

Fbxo2CreERT2: A new model for targeting cells in the neonatal and mature inner ear.

Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals.

Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis.

Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal

Collaborators (3)

Tanner Monroe

Chenghang Zong

Andrew K. Groves

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