Michael Freeman

Assistant Professor

University of Minnesota

United States

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About

Michael Freeman is an Assistant Professor at the University of Minnesota, USA. His research encompasses enzyme–substrate interactions, bioinformatic profiling, and the biosynthesis of natural products. Recent articles include studies on α-N-methyltransferase regiospecificity and the discovery of Borosin catalytic strategies, highlighting his focus on protein architectures and microbiome-derived chemical diversity.

Articles (6)

Year:

2025

Year:

2024

Year:

2023

Year:

2022

Year:

2021

Year:

2020

Collaborators (3)

Shravan Dommaraju

Vanderbilt University

UNITED STATES

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Matthew Jensen

Associate Professor of Chemistry

Concordia University

UNITED STATES

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Eric J. N. Helfrich

GERMANY

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Michael Freeman

Research Interests

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Articles (6)

α‐N‐Methyltransferase regiospecificity is mediated by proximal, redundant enzyme–substrate interactions

Discovery of Borosin Catalytic Strategies and Function through Bioinformatic Profiling

RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin α-N-methylated peptide natural product

Diverse Protein Architectures and α-N-Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters

Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli

Collaborators (3)

Shravan Dommaraju

Matthew Jensen

Eric J. N. Helfrich

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