Michael Gale

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University of Washington

United States

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Recent Grants

Grant: Close

Development of novel isoflavone drugs as broad spectrum antivirals

Open Date: 2016-06-22

Close Date: 2018-05-31

Grant: Close

The Host Response to Hepatitis C Virus

Open Date: 2016-03-01

Close Date: 2021-02-28

Grant: Close

Targeting IRFs for immune adjuvant enhancement of vaccine immunogenicity

Open Date: 2014-09-01

Close Date: 2019-09-01

Grant: Close

DEVELOPMENT OF KIN-1148 AS A NOVEL INNATE IMMUNE ADJUVANT SYSTEM FOR EMERGING RNA VIRUS VACCINES

Open Date: 2013-09-01

Close Date: 2017-09-01

Grant: Close

Nonhuman Primate Core Functional Genomics Laboratory for AIDS Vaccine Research and Development

Open Date: 2013-07-01

Close Date: 2017-06-01

Articles (14)

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2025

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2025

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2024

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2024

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2023

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2023

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2023

ZIKV isolates are classified under African or Asian lineages. Infection with emerging Asian lineage-derived ZIKV strains is associated with increased incidence of neurological symptoms that were not previously reported during infection with African or preemergent Asian lineage viruses.

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2023

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2023

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2022

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2022

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2022

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2022

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2021

Collaborators (18)

Xinxia Peng

College of Veterinary Medicine, North Carolina State University

UNITED STATES

Michael Gale

Research Interests

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Recent Grants

Articles (14)

Synthetic RIG-I-Agonist RNA Induces Death of Hepatocellular Carcinoma Cells

Enhanced antiviral innate immunity supports the bat reservoir of Marburg virus

Unraveling the Complexity of Chikungunya Virus Infection Immunological and Genetic Insights in Acute and Chronic Patients

Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques

Dynamics of SARS-CoV-2 VOC Neutralization and Novel mAb Reveal Protection against Omicron

COVID-19 Antigen Results Correlate with the Quantity of Replication-Competent SARS-CoV-2 in a Cross-Sectional Study of Ambulatory Adults during the Delta Wave

Expression of Envelope Protein Encoded by Endogenous Retrovirus K102 in Rheumatoid Arthritis Neutrophils.

Viral Protein Accumulation of Zika Virus Variants Links with Regulation of Innate Immunity for Differential Control of Viral Replication, Spread, and Response to Interferon

Orthohantavirus Replication in the Context of Innate Immunity

A C57BL/6 Mouse Model of SARS-CoV-2 Infection Recapitulates Age- and Sex-Based Differences in Human COVID-19 Disease and Recovery

Single-Cell–Based High-Throughput Ig and TCR Repertoire Sequencing Analysis in Rhesus Macaques

Alternative splicing and genetic variation of mhc-e: implications for rhesus cytomegalovirus-based vaccines

Biological functions of DEAD/DEAH-box RNA helicases in health and disease

Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes

Collaborators (18)

Xinxia Peng

Isaac Barber-Axthelm

Paul K. Drain

Brian Shaw

Michael Davis

Ana C. Maretti-Mira

Alexander L. Greninger

Rayan Najjar

Warren Ladiges

Tomas Mustelin

Yuan-Po Tu

Shreeram Akilesh

Lucy Golden-Mason

Matthew Burchill

Anna Wald

Ralph Baric

Judith Wasserheit

Allan Kirk

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