Michael Heneka

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Full prof and Director

University of Bonn

Germany

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About

Michael Heneka is a Full Professor and Director at the University of Bonn, Germany. His research interests primarily focus on neuroinflammation and its role in neurodegenerative diseases, with a recent emphasis on Alzheimer’s disease and related cognitive impairments. He has published numerous articles exploring brain networks, biomarkers, and therapeutics, contributing significantly to the understanding of neurobiological mechanisms in conditions such as Alzheimer's and amyotrophic lateral sclerosis.

Recent Grants

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Metaflammation-induced acceleration of neurodegeneration (P15)

Open Date: 2021-01-01

Close Date:

Grant: Close

EXC 2151: ImmunoSensation2 - the immune sensory system

Open Date: 2019-01-01

Close Date:

Grant: Close

Multiplexed point-of-care testing for inflammatory miRNA and neurotransmitter profiling in Alzheimer’s disease diagnostics

Open Date: 2019-01-01

Close Date:

Grant: Close

Role of inflammasomes in Alzheimer's Disease

Open Date: 2018-08-15

Close Date: 2023-04-30

Grant: Close

Mechanisms of Neuronal Dysfunction and Death in Sepsis-induced Cognitive Impairment

Open Date: 2016-01-01

Close Date: 2020-12-31

Articles (20)

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Collaborators (12)

Henning Boecker

University Hospital Bonn

GERMANY

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Christoffer Clemmensen

Københavns Universitet

DENMARK

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Christina Ising

GERMANY

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Felix Hernandez

Associate Professor

Universidad Autónoma de Madrid

SPAIN

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Ioanna Markaki

Karolinska Institutet

SWEDEN

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Gabriele Siciliano

Full Professor

University of Pisa

ITALY

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Vanessa Burholt

Professor of Gerontology

University of Auckland

NEW ZEALAND

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Carlo Custodero

Assistant professor

University of Bari Aldo Moro

ITALY

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Sofia Bergström

KTH Royal Institute of Technology

SWEDEN

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Sergio Castro-Gomez

University Hospital Bonn

GERMANY

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Tatsuya Manabe

Assistant Professor

Nagoya University

JAPAN

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Jose Luis Royo

University of Malaga

SPAIN

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Michael Heneka

Research Interests

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About

Recent Grants

Articles (20)

Incretin-based therapeutics for the treatment of neurodegenerative diseases

Locus coeruleus integrity correlates with plasma soluble Axl levels in Alzheimer's disease patients

Hidden networks in the brain

Neuroinflammatory fluid biomarkers in patients with Alzheimer’s disease: a systematic literature review

Cognitive capacity in amyotrophic lateral sclerosis: the value of diagnostic markers in cerebrospinal fluid and the influence of nutrition and pulmonary function

Ablation of CCL17‐positive hippocampal neurons induces inflammation‐dependent epilepsy

Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation

Zooming in on brain inflammation in Alzheimer’s disease

The role of leukocytes in cognitive impairment due to long‐term exposure to fine particulate matter: A large population‐based mediation analysis

The impact of neuroinflammation on neuronal integrity

Characterizing microglial senescence: Tau as a key player

NLRP3‐directed antisense oligonucleotides reduce microglial immunoactivities in vitro

p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease

Inflammasome activation in neurodegenerative diseases

Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing

Teaching an old dog new tricks: serum troponin T as a biomarker in amyotrophic lateral sclerosis

Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid‐binding protein 3 and ferritin to neurodegeneration and neuroinflammation

Long-term exposure to fine particulate matter, lung function and cognitive performance: A prospective Dutch cohort study on the underlying routes.

Collaborators (12)

Henning Boecker

Christoffer Clemmensen

Christina Ising

Felix Hernandez

Ioanna Markaki

Gabriele Siciliano

Vanessa Burholt

Carlo Custodero

Sofia Bergström

Sergio Castro-Gomez

Tatsuya Manabe

Jose Luis Royo

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