Michael Nielsen

Professor

University of Copenhagen

Denmark

Research Interests

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About

Michael Nielsen is a Professor at the University of Copenhagen, Denmark. His research areas focus on multi-omics characterizations, DNA damage signaling, and the dynamics of chromatin proteins. Recent articles authored by Professor Nielsen include studies on olaparib resistance in breast cancer, ubiquitin signaling processes, and proteomics related to RNA-binding proteins in neurodegenerative models.

Articles (16)

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2021

Collaborators (25)

Simon Rasmussen

Professor

University of Copenhagen

DENMARK

Michael Nielsen

Research Interests

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About

Articles (16)

Quantitative Chromatin Protein Dynamics During Replication Origin Firing in Human Cells

Multi-omics characterization of acquired Olaparib resistance in BRCA1 and BRCA2 mutant breast cancer cell lines

VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.

ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines

The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure

Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington’s disease

Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3

Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling

Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1

Characterizing citrullination by mass spectrometry-based proteomics

Waves of sumoylation support transcription dynamics during adipocyte differentiation.

SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway.

Temporal and Site-Specific ADP-Ribosylation Dynamics upon Different Genotoxic Stresses

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome.

Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4.

Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation.

Collaborators (25)

Simon Rasmussen

Oana Palasca

Pierre Chymkowitch

Andreas Mund

Agnete Kirkeby

Christian R. O. Bartling

Ronald Hay

Julien P Duxin

Jens Bukh

Agnieszka Gambus

Zita Fábián

Antonio Ariza

Alexandra Stripp Rebak

Michael Lisby

Troels Scheel

Abhishek Bharwadwaj Sharma

Ying Liu

Ivo Hendriks

Laura Massarenti

Irene Gallina

Jakob Nilsson

Guillermo Montoya

Hemmo Meyer

David Humphreys

Christian Friberg Nielsen

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