Michael O'Donovan

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Professor of Psychiatric Genetics

Cardiff University

United Kingdom

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About

Michael O'Donovan is a Professor of Psychiatric Genetics at Cardiff University, UK. His research focuses on the genetic underpinnings of psychiatric disorders, including schizophrenia, bipolar disorder, and major depressive disorder. He has contributed to significant advancements in understanding risk genes and the genomic implications of these conditions through various studies and analyses.

Recent Grants

Grant: Close

Integrating genetic, clinical and phenotypic data to advance stratification, prediction and treatment in mental health.

Open Date: 2018-03-30

Close Date: 2020-03-30

Grant: Close

Molecular Genetic Studies of Schizophrenia

Open Date: 2016-12-01

Close Date: 2021-11-30

Grant: Close

Preterm birth and neuropsychiatric genetic risks: a pilot investigation

Open Date: 2016-08-31

Close Date: 2019-02-28

Grant: Close

5/7 Psychiatric Genomics Consortium: Finding actionable variation

Open Date: 2016-06-20

Close Date: 2021-03-31

Grant: Close

Pathways to psychosis: Investigating environmental, cognitive and genetic mechanisms underlying development of psychotic experiences in young adults

Open Date: 2015-05-31

Close Date: 2020-02-29

Articles (19)

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2021

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2021

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2021

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2020

Collaborators (23)

Cathryn Lewis

King’s College London

UNITED KINGDOM

Michael O'Donovan

Research Interests

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About

Recent Grants

Articles (19)

Prioritizing effector genes at trait-associated loci using multimodal evidence

Whole-exome sequencing analysis identifies risk genes for schizophrenia

Genomics of schizophrenia, bipolar disorder and major depressive disorder

Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems

Common risk alleles for schizophrenia within the major histocompatibility complex predict white matter microstructure

Assessing the validity of a self-reported clinical diagnosis of schizophrenia

The genetics of cognition in schizophrenia

Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia

Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer’s disease through polygenic risk and RNA sequencing

The dynamic interplay between sleep and mood: an intensive longitudinal study of individuals with bipolar disorder

Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count

Genomic findings in schizophrenia and their implications

Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk

Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity

Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c

Sex differences in anxiety and depression in children with attention deficit hyperactivity disorder: Investigating genetic liability and comorbidity

Genetic association of FMRP targets with psychiatric disorders

Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders

A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder

Collaborators (23)

Cathryn Lewis

Nicholas Bray

Jon Heron

Christiaan de Leeuw

Ian Jones

Marijn Schipper

Kerrie Thomas

Nikki Hubers

James Walters

Siobhan Lock

Peter Holmans

Amy Shakeshaft

Joanna Martin

Sophie Smart

Lisa Jones

Darren Cameron

Kate Tilling

Neil Harrison

Olga Eyre

Kate Langley

Bernardo de Azevedo Pinto Castro Maciel

Valentina Escott-Price

Matt Jones

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