Michael Overduin

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Professor

University of Alberta

Canada

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Recent Grants

Grant: Close

Cure Cancer: Technology, Innovation and Medicine

Open Date: 2016-11-01

Close Date: 2018-01-31

Grant: Close

Structure-aided discovery of kinase inhibitors as targeted therapeutic agents for breast cancer

Open Date: 2016-11-01

Close Date: 2019-05-01

Grant: Close

Equipping NANUC, Canada's National NMR Facility, for Discovery Science

Open Date: 2015-11-24

Close Date:

Grant: Close

Understanding phopspholipid homeostasis in Gram-negative bacteria

Open Date: 2015-03-02

Close Date: 2020-03-01

Grant: Close

Structure-aided discovery of kinase inhibitors as targeted therapeutic agents for breast Cancer

Open Date: 2014-07-22

Close Date: 2017-01-31

Articles (12)

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (3)

Troy A. Kervin

University of Alberta

CANADA

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Khaled Barakat

University of Alberta

CANADA

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Gary Middleton

Professor of Medical Oncology

University of Birmingham

UNITED KINGDOM

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Michael Overduin

Research Interests

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Recent Grants

Articles (12)

Recognition and remodeling of endosomal zones by sorting nexins

Membranes are functionalized by a proteolipid code

SARS-CoV-2 Omicron Subvariants Balance Host Cell Membrane, Receptor, and Antibody Docking via an Overlapping Target Site

Discovery of allosteric SHP2 inhibitors through ensemble-based consensus molecular docking, endpoint and absolute binding free energy calculations

Transmembrane Membrane Readers form a Novel Class of Proteins That Include Peripheral Phosphoinositide Recognition Domains and Viral Spikes

Progressive membrane-binding mechanism of SARS-CoV-2 variant spike proteins

Multifaceted membrane binding head of the SARS-CoV-2 spike protein

Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer

Effects of Specific Inhibitors for CaMK1D on a Primary Neuron Model for Alzheimer’s Disease

Structures and Dynamics of Native-State Transmembrane Protein Targets and Bound Lipids

Regulation of the Phosphoinositide Code by Phosphorylation of Membrane Readers

Multisite interactions of prions with membranes and native nanodiscs

Collaborators (3)

Troy A. Kervin

Khaled Barakat

Gary Middleton

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