Michael Zhu

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Professor

The University of Texas Health Science Center at Houston

United States

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Michael Zhu is a Professor at the University of Texas Health Science Center at Houston, USA. His research focuses on calcium channels and their role in neuronal development, pain mechanisms, and ion channel regulation. Recent articles co-authored by him explore topics such as TRPC channel function in limbic behavior, analgesic mechanisms of TRPV1, and the implications of SUMOylation in actin dynamics.

Recent Grants

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Mechanism of ASIC1a-mediated acidosis brain damage in stroke

Open Date: 2015-01-01

Close Date: 2016-12-01

Grant: Close

Excitatory neurotransmission by PTX-sensitive G proteins

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Close Date:

Articles (19)

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2025

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2022

Collaborators (7)

Darren Boehning

Professor and Head

Cooper Medical School of Rowan University

UNITED STATES

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werner geldenhuys

Professor of Pharmaceutical Sciencs

West Virginia University

UNITED STATES

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Steven Prescott

Professor

University of Toronto

CANADA

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Travis Moore

Assistant Professor

The University of Texas Health Science Center at Houston

UNITED STATES

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Askar Akimzhanov

The University of Texas Health Science Center at Houston

UNITED STATES

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Israel Sekler

Ben-Gurion University of the Negev

ISRAEL

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Jamie McCall

Chief Scientist

ExesaLibero Pharma, Inc.

UNITED STATES

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Michael Zhu

Research Interests

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Recent Grants

Articles (19)

Targeting TRPC channels for control of arthritis-induced bone erosion

TRPC4 regulates limbic behavior and neuronal development by stabilizing dendrite branches through actomyosin-driven integrin activation

Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel

Druggable site near the upper vestibule determines the high affinity and P2X3 homotrimer selectivity of sivopixant/S‐600918 and its analogue DDTPA

Druggable site near the upper vestibule determines the high affinity and P2X3 homotrimer selectivity of sivopixant/S-600918 and its analogue DDTPA

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family

Readiness of nociceptor cell bodies to generate spontaneous activity results from background activity of diverse ion channels and high input resistance

TRPV1 analgesics disturb core body temperature via a biased allosteric mechanism involving conformations distinct from that for nociception

N-terminal α-amino SUMOylation of cofilin-1 is critical for its regulation of actin depolymerization

Total flavone of flowers of Abelmoschus manihot (L.) Medic inhibits the expression of adhesion molecules in primary mesenteric arterial endothelial cells and ameliorates dextran sodium sulphate-induced ulcerative colitis in mice

Expression and functions of transient receptor potential channels in liver diseases

N-terminal a-amino SUMOylation of cofilin-1 is critical for its regulation of actin depolymerization

TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect G q/11 –G i/o coincidence signals of variable strengths

Glutamine Produces Ammonium to Tune Lysosomal pH and Regulate Lysosomal Function

Transient Receptor Potential Channels in Cardiovascular and Renal Diseases

Dynamic S-acylation of the ER-resident protein stromal interaction molecule 1 (STIM1) is required for store-operated Ca2+ entry

The Three Two-Pore Channel Subtypes from Rabbit Exhibit Distinct Sensitivity to Phosphoinositides, Voltage, and Extracytosolic pH

Identification of an arthropod molecular target for plant-derived natural repellents

ASIC1a senses lactate uptake to regulate metabolism in neurons

Collaborators (7)

Darren Boehning

werner geldenhuys

Steven Prescott

Travis Moore

Askar Akimzhanov

Israel Sekler

Jamie McCall

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