Michelle Guignet

Acting Assistant Professor

University of Washington

United States

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Michelle Guignet is an Acting Assistant Professor at the University of Washington, USA. Her research focuses on epilepsy, particularly in the areas of therapeutic interventions, the effects of antiseizure medications, and the relationship between gut health and seizure activity. Recent articles highlight her work on community pharmacist interventions and innovative dosing paradigms for epilepsy treatment.

Articles (14)

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2025

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2024

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2020

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2020

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2020

Collaborators (4)

Michael Sperling

Professor

Thomas Jefferson University

UNITED STATES

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Adrian Rabinowicz

UNITED STATES

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Douglas Rowland

College of Engineering

UNITED STATES

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Pamela Lein

Professor of Neurotoxicology

University of California Davis School of Veterinary Medicine

UNITED STATES

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Michelle Guignet

Research Interests

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Articles (14)

Potential for Therapeutic Alteration of the Underlying Biology of Epilepsy

Challenging the preclinical paradigm: Adverse effects of antiseizure medicines in male rats with drug‐resistant epilepsy

Intestinal dysbiosis alters acute seizure burden and antiseizure medicine activity in Theiler's virus model of encephalitis

A community pharmacist intervention for people living with epilepsy

Community Pharmacist-Centered training program improves confidence in delivering epilepsy care

Development of a novel dosing paradigm to model diazepam rescue therapy in preclinical seizure and epilepsy models

Temporal relationship between levetiracetam nonadherence and breakthrough seizures in a preclinical model of temporal lobe epilepsy

Novel image analysis tool for rapid screening of cell morphology in preclinical animal models of disease

Perampanel’s forgiveness factor in a variable medication adherence paradigm in a rat model of chronic epilepsy

Repurposing dimethyl fumarate as an antiepileptogenic and disease-modifying treatment for drug-resistant epilepsy

Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate

Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate

The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity

Cenobamate (XCOPRI): Can preclinical and clinical evidence provide insight into its mechanism of action?

Collaborators (4)

Michael Sperling

Adrian Rabinowicz

Douglas Rowland

Pamela Lein

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