Michelle Gumz
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Recent Grants
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Modulation of the renal aldosterone endothelin feedback system by the clock protein PER1
Open Date: 2021-09-23
Close Date: 2022-08-31
Grant: Close
17th International Conference on Endothelin: Physiology, Pathophysiology and Therapeutics
Open Date: 2021-08-15
Close Date: 2022-08-14
Grant: Close
Kidney-specific and sex-dependent regulation of blood pressure by the circadian clock protein BMAL1
Open Date: 2019-07-01
Close Date: 2024-06-30
Grant: Close
Kidney-specific and sex-dependent regulation of blood pressure by the circadian clock protein BMAL1
Open Date: 2019-04-01
Close Date: 2024-06-30
Grant: Close
Per1 and the kidney clock in hypertension
Open Date: 2017-09-15
Close Date: 2023-05-31
Articles (9)
Year:
2024
Year:
2023
Year:
2023
Dysregulation of blood pressure (BP) circadian rhythm is associated with metabolic, cardiovascular, and kidney diseases. Our study provides experimental evidence demonstrating, for the first time, that renal tubule serum- and glucocorticoid-induced kinase 1 ( SGK1) plays an essential role in inducing the BP surge. Inhibitors and activators of SGK1 signaling are parts of several therapeutic strategies. Our findings highlight the importance of the drug intake timing to be in phase with SGK1 function to avoid dysregulation of BP circadian rhythm.
Year:
2023
Year:
2022
Year:
2022
Year:
2022
Year:
2022
Year:
2021
Collaborators (11)
Olivier Staub
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Rajesh Mohandas
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Amy Rogers
Academic, Clinical Lecturer (Teaching and Research)
University of Dundee
Lama Al-Qusairi
University of Lausanne
Michelle L. Gumz
University of Florida
Karyn Esser
University of Florida
Karen Gamble
Professor and Vice Chair of Basic Research
The University of Alabama
Andrew Chuanyin Liu
Associate-Full Professor
University of Florida
Daichi Shimbo
Columbia University Irving Medical Center
Yabing Chen
Professor
The University of Alabama
Andrew Bryant
Associate Professor
University of Florida College of Medicine
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