Miguel Garcia-Diaz

Associate Professor

Stony Brook University

United States

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Dr. Miguel Garcia-Diaz is an Associate Professor at Stony Brook University in the United States. His research focuses on areas including viral replication mechanisms, mitochondrial function, and enzymatic processes in Mycobacterium tuberculosis. Recent publications highlight his work on ribonucleotide incorporation by SARS-CoV-2, interactions of aurintricarboxylic acid with viral targets, and the role of mitochondrial transcription factors.

Articles (8)

Year:

2023

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2022

Year:

2022

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (5)

nicole sampson

Distinguished Professor and Dean College of Arts and Sciences

Stony Brook University

UNITED STATES

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Sara Villa Hernandez

King’s College London

UNITED KINGDOM

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Francesco CUCCA

Full Professor of Medical Genetics

University of Sassari

ITALY

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Michele Giannattasio

Head of IFOM ETS Electron Microscopy Unit- DNA/Single Molecules

ITALY

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Aidan Doherty

University of Sussex

UNITED KINGDOM

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Miguel Garcia-Diaz

Research Interests

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Articles (8)

Fidelity of Ribonucleotide Incorporation by the SARS-CoV-2 Replication Complex.

Characterization of Aurintricarboxylic Acid (ATA) Interactions with Plasma Transporter Protein and SARS-CoV-2 Viral Targets: Correlation of Functional Activity and Binding Energetics.

A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM).

Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.

Enzymatic β-Oxidation of the Cholesterol Side Chain in <i>Mycobacterium tuberculosis</i> Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA.

A549 cells contain enlarged mitochondria with independently functional clustered mtDNA nucleoids.

Post-translational Succinylation of <i>Mycobacterium tuberculosis</i> Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA.

Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.

Collaborators (5)

nicole sampson

Sara Villa Hernandez

Francesco CUCCA

Michele Giannattasio

Aidan Doherty

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