Miguel Xavier Fernandes

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Senior Lecturer

Karlstad University

Sweden

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About

Miguel Xavier Fernandes is a Senior Lecturer at Karlstad University, Sweden. His research focuses on pharmacological profiling, the development of inhibitors for cancer treatments, and the investigation of enzyme selectivity in neurological applications. Recent publications include studies on various bioactive compounds and their roles in cancer therapy and neurodegenerative diseases.

Recent Grants

Grant: Close

TheraPanc - New Therapeutic Strategies for the Treatment of Pancreatic Cancer

Open Date: 2020-01-01

Close Date: 2022-09-01

Grant: Close

TheraPanc - New Therapeutic Strategies for the Treatment of Pancreatic Cancer

Open Date: 2020-01-01

Close Date:

Grant: Close

FARMACAN - Early pharmacological profile of marine natural products from the Canary biodiversity

Open Date: 2020-01-01

Close Date: 2021-09-01

Grant: Close

FARMACAN - Early pharmacological profile of marine natural products from the Canary biodiversity

Open Date: 2020-01-01

Close Date:

Grant: Close

Development of a new technology for acceleration of preclinical drug trials.

Open Date: 2020-01-01

Close Date: 2021-06-30

Articles (10)

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (10)

José M. Padrón

Full Professor

Universidad de la Laguna

SPAIN

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Jörgen Samuelsson

Karlstad University

SWEDEN

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Macarena Martínez-Bailén

SPAIN

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José G. Fernandez-Bolaños

Universidad de Sevilla

SPAIN

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Pedro Brandão

Assistant Professor

Egas Moniz Cooperativa de Ensino Superior CRL

PORTUGAL

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Óscar López

Associate Professor

Universidad de Sevilla

SPAIN

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Alessio Nocentini

University of Florence

ITALY

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José Antonio Gómez Vidal

Universidad de Granada

SPAIN

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Angel Luis Pey

Assistant Professor

Universidad de Granada

SPAIN

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Magne Sydnes

Professor

University of Stavanger

NORWAY

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Miguel Xavier Fernandes

Research Interests

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About

Recent Grants

Articles (10)

Coumarin–azasugar–benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth

Modelling the pH dependent retention and competitive adsorption of charged and ionizable solutes in mixed-mode and reversed-phase liquid chromatography

Early pharmacological profiling of isatin derivatives as potent and selective cytotoxic agents

Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers

Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors

Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease

New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production

A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)

A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors

2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases

Collaborators (10)

José M. Padrón

Jörgen Samuelsson

Macarena Martínez-Bailén

José G. Fernandez-Bolaños

Pedro Brandão

Óscar López

Alessio Nocentini

José Antonio Gómez Vidal

Angel Luis Pey

Magne Sydnes

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