Minna Kaikkonen

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Professor of Cardiovascular Genomics

University of Eastern Finland

Finland

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About

Minna Kaikkonen is a Professor of Cardiovascular Genomics at the University of Eastern Finland. Her research primarily focuses on the genetic and epigenetic factors influencing cardiovascular diseases, with recent publications addressing topics such as atherosclerosis, genetic variation in obesity, and the functional genomics of coronary artery disease. She actively explores the impact of mitochondrial signaling and mechanosensitive elements in vascular health. Professor Kaikkonen's work contributes significantly to bridging the gap between genomic research and clinical applications in cardiovascular medicine.

Recent Grants

Grant: Close

Macrophage phenotypic polarization during atherogenesis in disease-associated tissues

Open Date: 2020-09-01

Close Date: 2024-08-01

Grant: Close

Enhancers Decoding the Mechanisms Underlying CAD Risk

Open Date: 2019-01-01

Close Date: 2023-12-01

Grant: Close

Gene Regulatory Mechanisms Governing Atherogenesis

Open Date: 2015-08-01

Close Date: 2021-12-01

Articles (18)

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2021

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2021

Collaborators (18)

Johanna P Laakkonen

University of Eastern Finland

FINLAND

Minna Kaikkonen

Research Interests

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About

Recent Grants

Articles (18)

Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis

Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial

Special issue: Decoding atherosclerosis: Epigenetics and functional genomics

Technological advancements in functional interpretation of genome‐wide association studies (<scp>GWAS</scp>) findings: bridging the gap to clinical translation

Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations

Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro

Genetic variation drives differences in obesity-related gene regulation

Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells

Exploring the genetic basis of coronary artery disease using functional genomics

ApoA-I Nanotherapy Rescues Postischemic Vascular Maladaptation by Modulating Endothelial Cell and Macrophage Phenotypes in Type 2 Diabetic Mice

Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer&rsquo;s Disease Patients

The Power of Single-Cell RNA Sequencing in eQTL Discovery

Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis

Genomic Landscapes of Noncoding RNAs Regulating VEGFA and VEGFC Expression in Endothelial Cells

Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models.

Pharmacological or TRIB3-Mediated Suppression of ATF4 Transcriptional Activity Promotes Hepatoma Cell Resistance to Proteasome Inhibitor Bortezomib.

Polycomb Repressive Complex 2 Regulates Genes Necessary for Intestinal Microfold Cell (M Cell) Development.

Collaborators (18)

Johanna P Laakkonen

Mustafa Beter

Keijo Viiri

Debora Sobreira

Alan Mackay-Sim

Casey Romanoski

Karoline Kollmann

Redouane Aherrahrou

Pierre Moreau

Terhi Rintakangas

Christian Hengstenberg

Katja M. Kanninen

Marion Mussbacher

Alice Assinger

MD SHARIF IQBAL

Alfredo Ramirez

Simone Avesani

Rosalba Giugno

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Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients