Miquel Vila

Catalan Institution for Research and Advanced Studies (ICREA)

Spain

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Articles (19)

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2025

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Collaborators (14)

Jesús Giraldo

Professor (Catedrático de Universidad)

University of Barcelona

SPAIN

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Michele Morari

University of Ferrara

ITALY

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Ariadna Recasens

MONASH UNIVERSITY

AUSTRALIA

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Maria D Ganfornina

SPAIN

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Iria Carballo-Carbajal

Vall d'Hebron Research Institute

SPAIN

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Marta González Sepúlveda

Lecturer in the intercollegiate Bachelor’s Programme in Physiotherapy

SPAIN

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Helena Xicoy

Vall d'Hebron Institut de Recerca

SPAIN

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Irena Lassot

INSERM

FRANCE

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Marta Martinez-Vicente

Vall d'Hebron Institut de Recerca

SPAIN

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Carles Gil

Full professor

University of Barcelona

SPAIN

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Jordi Ortiz

Associate Professor

SPAIN

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Valentin Coppola-Segovia

Aarhus University

DENMARK

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Eleanna Kara

Assistant Professor

Rutgers University

UNITED STATES

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Nicolas P. Rougier

Institut des Maladies Neurodégénératives

FRANCE

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Miquel Vila

Research Interests

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Articles (19)

ZSCAN21 mediates the pathogenic transcriptional induction of α-synuclein in cellular and animal models of Parkinson’s disease

LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson’s disease model

Standardised TruAI Automated Quantification of Intracellular Neuromelanin Granules in Human Brain Tissue Sections

Differential Pathological Dynamics triggered by distinct Parkinson patient-derived α-synuclein extracts in non-human primates

Neuromelanin and selective neuronal vulnerability to Parkinson’s disease

Single-cell transcriptomics for immune profiling of cerebrospinal fluid in neurological diseases

Longitudinal neuromelanin changes in prodromal and early Parkinson’s disease in humans and rat model

Age-dependent progression from clearance to vulnerability in the early response of periventricular microglia to α-synuclein toxic species

Autophagy and Protein Quality Control in Parkinson's Disease

Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits

Spontaneous changes in brain striatal dopamine synthesis and storage dynamics ex vivo reveal end-product feedback-inhibition of tyrosine hydroxylase.

Validation of a Reversed Phase UPLC-MS/MS Method to Determine Dopamine Metabolites and Oxidation Intermediates in Neuronal Differentiated SH-SY5Y Cells and Brain Tissue.

Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice

Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease

Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys

Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

LRRK2 in Parkinson disease: challenges of clinical trials.

Collaborators (14)

Jesús Giraldo

Michele Morari

Ariadna Recasens

Maria D Ganfornina

Iria Carballo-Carbajal

Marta González Sepúlveda

Helena Xicoy

Irena Lassot

Marta Martinez-Vicente

Carles Gil

Jordi Ortiz

Valentin Coppola-Segovia

Eleanna Kara

Nicolas P. Rougier

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