MIRELA KUKA

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Assistant Professor

Vita-Salute San Raffaele University

Italy

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About

Dr. Mirela Kuka is an Assistant Professor at Vita-Salute San Raffaele University in Italy. Her research focuses on the immune system, particularly in the areas of T cell differentiation and functionality, B cell responses, and the implications of viral infections. Recent publications include studies on TDC cells in immunity, the effects of LSD1 inhibition on T cell therapy, and the regulation of B cell class switch recombination.

Recent Grants

Grant: Close

PRIN2017

Open Date: 2019-01-01

Close Date: 2023-01-01

Grant: Close

Scientific Independence of Young Researchers (SIR)

Open Date: 2015-09-01

Close Date: 2020-09-01

Grant: Close

INVEST-COFUND International Postdoctoral Programme

Open Date: 2013-09-01

Close Date: 2015-09-01

Articles (13)

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2025

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2024

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2024

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (5)

Christoph Heuser-Loy

GERMANY

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Philippe Bousso

FRANCE

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Ruth Herbst

Assoc. Prof. Dr.

Medical University of Vienna

AUSTRIA

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Luca G. Guidotti

Full Professor

Università Vita Salute San Raffaele

ITALY

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Raffaele De Francesco

Professore Ordinario di Microbiologia (BIO/19)

Università degli Studi di Torino

ITALY

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MIRELA KUKA

Research Interests

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Contact this professor

About

Recent Grants

Articles (13)

The dual nature of TDC – bridging dendritic and T cells in immunity

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness

Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination.

The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling

A fluorescent reporter model for the visualization and characterization of T<sub>DC</sub>.

B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation.

Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion

Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability.

Heterogeneity in antiviral B cell responses: Lessons from the movies*

miR-21 sustains CD28 signalling and low-affinity T-cell responses at the expense of self-tolerance.

Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4<sup>+</sup> T cells.

The Suppressive Attitude of Inflammatory Monocytes in Antiviral Antibody Responses.

The elusive identity of CXCR5+ CD8 T cells in viral infection and autoimmunity: Cytotoxic, regulatory, or helper cells?

Collaborators (5)

Christoph Heuser-Loy

Philippe Bousso

Ruth Herbst

Luca G. Guidotti

Raffaele De Francesco

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