Mitsuaki Hirose

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Assistant Professor

Seikei University

Japan

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About

Dr. Mitsuaki Hirose is an Assistant Professor at Seikei University in Japan. His research primarily focuses on enzymatic processes related to chlorophyll degradation, glycan synthesis, and the molecular understanding of glycan-related proteins. Recent publications highlight his work on magnesium dechelatase activity, the synthesis of N-glycan mimics, and the biosynthetic pathways of bacteriochlorophyll.

Recent Grants

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生体外における酵素反応場の作製による会合体形成過程の解明

Open Date: 2021-04-01

Close Date: 2024-03-01

Articles (19)

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2025

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2020

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2020

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2020

Collaborators (2)

Kiichiro Totani

Seikei University

JAPAN

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Yuichiro Kashiyama

Professor

University of Fukui

JAPAN

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Mitsuaki Hirose

Research Interests

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About

Recent Grants

Articles (19)

Synthesis of N-glycan mimics for investigating the influence of the N-acetyl group in core GlcNAc2 on the folded conformation

Development of a Calreticulin-targeting Glycan Ligand Based on a Hybrid Binding Concept

Stepwise self-organization of hydrogen-bonded fibers in a minimalist glucose-pyrene system via CH–π-stabilized “iotamers”

Chelatase activity of magnesium dechelatase associated with chlorophyll degradation

Enzymatic Activity of C-20 Methyltransferase BchU Evaluating Its Role in Bacteriochlorophyll <i>c</i> Biosynthetic Pathway

Preparation of natural high-mannose-type oligosaccharides (Glc1Man9GlcNAc2) with the asparagine-glycine-threonine as consensus sequence from chicken egg yolk

In vitro demetalation of central magnesium in various chlorophyll derivatives using Mg-dechelatase homolog from the chloroflexi Anaerolineae

Synthesis of C3-substituted chlorophyll-a derivatives fused by a π-conjugated E-ring and their physical properties with unique near-infrared absorption

Chemical Study of High-Mannose-Type Glycan-Related Proteins to Understand Their Functions at the Molecular Level

Predicted Structure of the BciC Enzyme Catalyzing the Removal of the C13<sup>2</sup>-Methoxycarbonyl Group for Biosynthesis of Chlorosomal Chlorophylls: A Mechanism for Dual Catalytic Functions of Hydrolysis and Decarboxylation inside Its Active Site

Chiral-phase HPLC separation of (divinyl-)protochlorophyllide-a enantiomers as key precursors in chlorophyll biosynthesis from their 132-stereoisomeric prime forms

In vitro reversible dehydration in C3-substituents of zinc chlorophyll analogs by BchF and BchV enzymes: Stereoselectivity and substrate specificity in the dehydration

Characterization of regioisomeric diterpenoid tails in bacteriochlorophylls produced by geranylgeranyl reductase from Halorhodospira halochloris and Blastochloris viridis

Detection of 132-carboxy-chlorin produced by the in vitro BciC enzymatic hydrolysis of zinc chlorophyllide

Physicochemical and biochemical properties of synthetic zinc 131-(un)substituted chlorophyll-a derivatives

In vitro hydrolysis of zinc chlorophyllide a homologues by a BciC enzyme

In vitro C132-dealkoxycarbonylations of zinc chlorophyll a derivatives including C132-substitutes by a BciC enzyme

BciC‐catalyzed C132‐demethoxycarbonylation of metal pheophorbide a alkyl esters

Synthesis of chlorophyll-a homologs by C132-substitutions and their physico- and biochemical properties

Collaborators (2)

Kiichiro Totani

Yuichiro Kashiyama

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