Mohamed Ezzelarab

Research Associate Professor

United States

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Dr. Mohamed Ezzelarab is a Research Associate Professor at the University of Pittsburgh Thomas E Starzl Transplantation Institute, USA. His research focuses on xenotransplantation and the immunological responses involved, as evidenced by his recent articles on T cell transcriptional changes, systemic inflammation in xenotransplant recipients, and the role of interleukin-6 in xenograft failure. He is also involved in studies concerning the histopathology of genetically-engineered pig organ transplants and regulatory T cells as potential cellular therapeutics.

Articles (11)

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (3)

WENSHENG ZHANG

Research Associate Professor of Surgery

Uniformed Services University of the Health Sciences

UNITED STATES

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Jeremy Foote

Associate Professor

The University of Alabama

UNITED STATES

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Takayuki Yamamoto

Associate Professor

Albany Medical Center

UNITED STATES

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Mohamed Ezzelarab

Research Interests

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Articles (11)

Distinct Pro‐Inflammatory Species‐Specific Transcriptional Changes in Human T Cells Following Pig Xenogeneic Stimulation

Systemic inflammation in the xenotransplant recipient (SIXR) can occur in the absence of pCMV infection

Tacrolimus before CTLA4Ig and rapamycin promotes vascularized composite allograft survival in MGH miniature swine.

Cardiac and Pulmonary Histopathology in Baboons Following Genetically-Engineered Pig Orthotopic Heart Transplantation.

The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure.

Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.

Ex Vivo Expanded Donor Alloreactive Regulatory T Cells Lose Immunoregulatory, Proliferation, and Antiapoptotic Markers After Infusion Into ATG-lymphodepleted, Nonhuman Primate Heart Allograft Recipients.

Non-human Primate Regulatory T Cells and Their Assessment as Cellular Therapeutics in Preclinical Transplantation Models.

What Therapeutic Regimen Will Be Optimal for Initial Clinical Trials of Pig Organ Transplantation?

Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons.

Generation and functional assessment of nonhuman primate regulatory dendritic cells and their therapeutic efficacy in renal transplantation.

Collaborators (3)

WENSHENG ZHANG

Jeremy Foote

Takayuki Yamamoto

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