Mohammad Anwar Hossain

Research Assistant Professor

University of North Carolina at Chapel Hill

United States

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Mohammad Anwar Hossain is a Research Assistant Professor at the University of North Carolina at Chapel Hill, USA. His research focuses on antiviral chemistry, particularly in the development of inhibitors targeting Chikungunya virus helicase and protease. Recent publications highlight the structural insights into viral targets and innovative screening approaches for therapeutic discovery.

Articles (10)

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2025

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2025

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2025

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2025

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2024

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2024

Collaborators (3)

Hans Oh

UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill

UNITED STATES

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Eugene N Muratov

University of North Carolina

UNITED STATES

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Timothy Willson

Professor

University of North Carolina at Chapel Hill

UNITED STATES

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Mohammad Anwar Hossain

Research Interests

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Articles (10)

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Chemical arsenal for helicase Hunters: Striking the toughest targets in antiviral research

Species-Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with In Vivo Antialphaviral Activity

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy

A soft-stiff patterned bioengineering model reveals kinase pathways driving directional cell migration in pulmonary arterial hypertension

Identification of Dihydropyrazolo[1,5-a]pyrazin-4(5H)-ones as Cyclic Products of β-Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity

Collaborators (3)

Hans Oh

Eugene N Muratov

Timothy Willson

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