Naoharu Takano

Tokyo Medical and Dental University

Japan

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Articles (11)

Year:

2024

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2023

Year:

2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (4)

Hirotsugu Hino

Assistant Professor

Nihon University School of Medicine

JAPAN

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Keisuke Miyazawa

Professor and Chairman

Tokyo Medical and Dental University

JAPAN

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MASAKI HIRAMOTO

Associate Professor

Tokyo Medical and Dental University

JAPAN

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Masahiko Kuroda

JAPAN

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Naoharu Takano

Research Interests

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Articles (11)

Vitamin K2 sensitizes the efficacy of venetoclax in acute myeloid leukemia by targeting the NOXA-MCL-1 pathway

Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics

p53 regulates lysosomal membrane permeabilization as well as cytoprotective autophagy in response to DNA-damaging drugs

Ricolinostat enhances adavosertib‑induced mitotic catastrophe in TP53‑mutated head and neck squamous cell carcinoma cells.

Lysosome‑targeted drug combination induces multiple organelle dysfunctions and non‑canonical death in pancreatic cancer cells.

Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics.

Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells

Induction of synergistic non-apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells.

BRCA1 degradation in response to mitochondrial damage in breast cancer cells.

Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization‑associated cell death.

Sequestosome 1 (p62) accumulation in breast cancer cells suppresses progesterone receptor expression via argonaute 2.

Collaborators (4)

Hirotsugu Hino

Keisuke Miyazawa

MASAKI HIRAMOTO

Masahiko Kuroda

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