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Nasim Sabouri

Associate Professor

Umeå Universitet Medicinska fakulteten

Sweden

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Research Interests

Biochemistry

70%

Pharmaceutical Chemistry

20%

Dna Nanotechnology

50%

Chemical Biology

40%

Photopharmacology

30%

Nucleic Acid Chemistry

30%

Heterocyclic Chemistry

30%

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Articles17

Photodynamic Therapy Using a Heavy-Atom-Free G-Quadruplex-Targeted Photosensitizer to Efficiently Regress Rhabdomyosarcoma Tumors In Vivo

Article Link

Year:

2025

CRISPR-Cas9 targeting of G-Quadruplex DNA in ADH1 promoter highlights its role in transcriptome and metabolome regulation

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Year:

2025

Organelle-Specific Thiochromenocarbazole Imide Derivative as a Heavy-Atom-Free Type I Photosensitizer for Biomolecule-Triggered Image-Guided Photodynamic Therapy

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Year:

2025

A Rationally Designed Azobenzene Photoswitch for DNA G‐Quadruplex Regulation in Live Cells

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Year:

2025

A Rationally Designed Azobenzene Photoswitch for DNA G‐Quadruplex Regulation in Live Cells

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Year:

2025

Harnessing Light for G-Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene Derivative

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Year:

2024

Parallel G-Quadruplex DNA Structures from Nuclear and Mitochondrial Genomes Trigger Emission Enhancement in a Nonfluorescent Nano-aggregated Fluorine–Boron-Based Dye

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Year:

2023

Correction: Light-induced in situ chemical activation of a fluorescent probe for monitoring intracellular G-quadruplex structures

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Year:

2023

A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression

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Year:

2023

Probing the folding pathways of four-stranded intercalated cytosine-rich motifs at single base-pair resolution

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Year:

2022

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

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Year:

2021

The RGG domain in the C-terminus of the DEAD box helicases Dbp2 and Ded1 is necessary for G-quadruplex destabilization

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Year:

2021

Light-induced in situ chemical activation of a fluorescent probe for monitoring intracellular G-quadruplex structures

Article Link

Year:

2021

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

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Year:

2020

The Relation Between Position and Chemical Composition of Bis‐Indole Substituents Determines Their Interactions with G‐Quadruplex DNA

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Year:

2020

A Light‐up Logic Platform for Selective Recognition of Parallel G‐Quadruplex Structures via Disaggregation‐Induced Emission

Article Link

Year:

2020

A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA

Article Link

Year:

2020

Collaborators11

Laura Abad Galán

Assistant professor

Universidad Complutense de Madrid

SPAIN

Abraha Kahsay

Umea University

SWEDEN

Ikenna Obi

Umea University

SWEDEN

Jonas von Hofsten

Senior Lecturer

Umeå University

SWEDEN

Marta Dudek (Ziemianek)

Assistant professor

Politechnika Wroclawska

POLAND

Jan Jamroskovic

Umea University

SWEDEN

Katarzyna Matczyszyn

Wroclaw University of Science and Technology

POLAND

Erik Chorell

Umea University

SWEDEN

Marco Deiana

Assistant Professor

University of Wrocław

POLAND

Juan J. Nogueira

Universidad Autónoma de Madrid

SPAIN

Elise Dumont

Full Professor in Chemistry

Université Côte d'Azur

FRANCE

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