Neil Vargesson

Professor in Developmental Biology

University of Aberdeen

United Kingdom

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Neil Vargesson is a Professor in Developmental Biology at the University of Aberdeen, UK. His research focuses on neuroinflammation, teratogenicity, and embryonic vascular development, as evidenced by his recent articles examining the effects of thalidomide and neurodegenerative disorders. Professor Vargesson's work also includes the synthesis of novel compounds and their biological activities, alongside exploring gene expression in developing tissues.

Articles (18)

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2025

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2021

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2020

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2020

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2020

Collaborators (9)

Jason A Horton

Assistant Professor

SUNY Upstate Medical University

UNITED STATES

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Julia Kozlitina

Associate Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Michael Gütschow

University of Bonn

GERMANY

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Lynda Erskine

Professor

University of Aberdeen

UNITED KINGDOM

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Elliot Glotfelty

Karolinska Institutet

SWEDEN

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David B Parkinson

University of Plymouth

UNITED KINGDOM

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Nigel Greig

Chief, Drug Design & Development Section

National Institute on Aging

UNITED STATES

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Sarah Westbury

University of Bristol

UNITED KINGDOM

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Marcella Reale

ITALY

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Neil Vargesson

Research Interests

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About

Articles (18)

Embryonic Vascular Dysgenesis: The Origin of Proximal Femoral Focal Deficiency

Monoterpenoid fluorophthalimide IMiDs that lack human cereblon binding: synthesis and anti-proliferative, anti-angiogenic and anti-inflammatory activities

Targeting neuroinflammation

Cereblon E3 ligase complex genes are expressed in tissues sensitive to thalidomide in chicken and zebrafish embryos but are unchanged following thalidomide exposure

Identification of lens-regulated genes driving anterior eye development

Thalidomide upper limb embryopathy – pathogenesis, past and present management and future considerations

A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders

Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury

Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5 kb from coding DNA

Teratogenicity and Reactive Oxygen Species after transient embryonic hypoxia

Considerations for future quantitative structure-activity relationship (QSAR) modelling for heavy metals

Genetic association and characterization of FSTL5 in isolated clubfoot

Knockdown of slit signaling during limb development leads to a reduction in humerus length

From the Farm to the Lab: How Chicken Embryos Contribute to the Field of Teratology

Lewis Wolpert (1929–2021)

Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

Positional Information—A concept underpinning our understanding of developmental biology

Role of cereblon in angiogenesis and in mediating the antiangiogenic activity of immunomodulatory drugs

Collaborators (9)

Jason A Horton

Julia Kozlitina

Michael Gütschow

Lynda Erskine

Elliot Glotfelty

David B Parkinson

Nigel Greig

Sarah Westbury

Marcella Reale

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