Nicholas Markham

Assistant Professor

Vanderbilt University Medical Center

United States

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Dr. Nicholas Markham is an Assistant Professor at Vanderbilt University Medical Center in the United States. His research primarily focuses on gastrointestinal cancer, exploring the roles of immune signaling, microbiota, and epithelial biology in colorectal and gastric tumors. Recent publications include studies on the protective effects of IL-17 signaling against Helicobacter pylori-induced gastric cancer and the dynamics of microenvironmental factors in carcinogenesis.

Articles (12)

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2024

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2021

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2021

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UNITED STATES

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Jeremy Goettel

Assistant Professor

Vanderbilt University Medical Center

UNITED STATES

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Emily Green

Vanderbilt University

UNITED STATES

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Nicholas Markham

Research Interests

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Articles (12)

Distinct roles for interleukin-23 receptor signaling in regulatory T cells in sporadic and inflammation-associated carcinogenesis

IL-17 signaling protects against Helicobacter pylori- induced gastric cancer

Cecum axis (CecAx) preservation reveals physiological and pathological gradients in mouse gastrointestinal epithelium

An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism

Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

Murine Intrarectal Instillation of Purified Recombinant Clostridioides difficile Toxins Enables Mechanistic Studies of Pathogenesis

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice

Fecal Microbiota Transplantation for Recurrent <i>Clostridioides difficile</i> Infection Associates With Functional Alterations in Circulating microRNAs

Clinically adaptable polymer enables simultaneous spatial analysis of colonic tissues and biofilms

Collaborators (8)

Anna Means

Cynthia L. Sears

Mariana Byndloss

Timothy Su

Borden Lacy

Heather Kroh

Jeremy Goettel

Emily Green

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